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Record W4416714235 · doi:10.1101/2025.11.24.690150

Separating faces in ARMS metabarcoding improves marine biodiversity monitoring: a comparison across protocols, experimental designs, and photographic surveys

2025· preprint· en· W4416714235 on OpenAlexaff
Anne Chenuil, Elyna Bouchereau, Térence Legrand, Virgile Calvert, Cécile Chemin, Sandrine Chenesseau, Dorian Guillemain, José Miguel Ortega, Anne Haguenauer, Michèle Leduc, Florent Marschal, Christian Marschal, Fatma Mirleau, Marjorie Selva, Laurent Vanbostal, Frédéric Zuberer, Pascal Mirleau, Laetitia Plaisance, Vincent Rossi, Sandrine Ruitton, Emese Meglécz, Vincent Dubut

Bibliographic record

VenuebioRxiv (Cold Spring Harbor Laboratory) · 2025
Typepreprint
Languageen
FieldEnvironmental Science
TopicEnvironmental DNA in Biodiversity Studies
Canadian institutionsCanadian Nautical Research Society
FundersEuropean Regional Development FundCentro para el Desarrollo Tecnológico IndustrialCentre de Coopération Internationale en Recherche Agronomique pour le DéveloppementAgence Nationale de la RechercheEuropean Space Agency
KeywordsEnvironmental DNASpecies richnessBiodiversityPoolingSampling (signal processing)Pipeline (software)Abundance (ecology)Ranking (information retrieval)Benchmark (surveying)

Abstract

fetched live from OpenAlex

Abstract Monitoring marine biodiversity requires approaches that capture its full complexity through space and time. DNA metabarcoding coupled with Autonomous Reef Monitoring Structures (ARMS) is increasingly used for this purpose, yet most applications still pool all sessile fractions and rarely benchmark molecular ouputs against photographic observations. Here, we combined photographic analysis with cytochrome c oxidase I (COI) metabarcoding across ten north-western Mediterranean sites to test, compare, and refine ARMS-based monitoring protocols. We first optimized laboratory procedures (DNA extraction and polymerase choice) and applied the control-driven, replicate-aware VTAM pipeline to minimize false positives and ensure full traceability. We then conducted the first face-by-face comparison of α- and β-diversity between imaging and eDNA in which each individual ARMS face was metabarcoded separately rather than pooled. Metabarcoding detected ∼15× higher site-level richness and revealed stronger correlations with geographic distance and environmental gradients, whereas photography provided complementary information on macro-taxa and surface cover. For metabarcoding, processing each face separately yielded much higher richness and markedly stronger β-diversity–distance correlations than with the NOAA pooling protocol, demonstrating that pooling inflates sampling variance resulting in a loss of the ecological signal. Grouping faces into five structural categories offered a more operational alternative while further increasing α-diversity and strengthening β-diversity correlations. Overall, our results show that retaining ARMS microhabitat structure is critical for maximizing metabarcoding performance. Using five structural sessile fractions per ARMS combined with a control-driven bioinformatic workflow provides a reproducible, scalable framework for long-term eDNA monitoring and early detection of biodiversity change.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.007
metaresearch head score (Gemma)0.012
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.007
Threshold uncertainty score0.040

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0070.012
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0010.000
Science and technology studies0.0010.001
Scholarly communication0.0010.001
Open science0.0010.002
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0030.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.042
GPT teacher head0.284
Teacher spread0.242 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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