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Record W4416717795 · doi:10.1097/md.0000000000046235

Seroprevalence of Toxocara spp. infection and its associated factors among children in Vietnam: A cross-sectional study

2025· article· en· W4416717795 on OpenAlexaff
Giao Huỳnh, Dung Quoc Phan, Tien Minh Tran, Duy Nguyen, Hau Viet Nguyen, Han Thi Ngoc Nguyen, L. Vo

Bibliographic record

VenueMedicine · 2025
Typearticle
Languageen
FieldImmunology and Microbiology
TopicParasitic Infections and Diagnostics
Canadian institutionsWind Energy Institute of Canada
Fundersnot available
KeywordsSeroprevalenceToxocariasisOdds ratioToxocara catiConfidence intervalVietnameseLogistic regressionToxocara canis

Abstract

fetched live from OpenAlex

Toxocariasis, caused by Toxocara canis and T cati (Toxocara spp.), is one of the 6 most neglected zoonotic diseases worldwide. Children are particularly vulnerable to this infection, which can lead to many negative health effects. This study determines the seroprevalence of Toxocara spp. and identifies associated factors among Vietnamese children. A cross-sectional study was conducted at Le Van Thinh Hospital, Vietnam, from June to October 2024. Data was collected through structured questionnaires and laboratory testing of blood samples using enzyme-linked immunosorbent assay. Multivariate logistic regression was used to assess the association between Toxocara spp. seroprevalence and potential associated factors, with an adjusted odds ratio (aOR) reported, and statistical significance was defined as P < .05. Among 216 children who met all criteria, 13.8% tested positive for Toxocara spp. Multivariate analysis revealed significant associations with pruritus (aOR = 2.64; 95% confidence interval [CI], 1.01-6.83; P = .045), limb pain (aOR = 6.77; 95% CI, 1.32-34.65; P = .022), consumption of raw vegetables (aOR = 2.40; 95% CI, 1.15-5.01; P = .019), inadequate handwashing before meals (aOR = 0.47; 95% CI, 0.23-0.85; P = .036), and habit of contact with dogs or cats (aOR = 2.21; 95% CI, 1.17-4.19; P = .014). The seroprevalence rate of Toxocara spp. among Vietnamese children was quite low. Children exhibiting pruritus and limb pain, combined with the consumption of raw vegetables, inadequate handwashing before meals, and a habit of contact with dogs or cats, should undergo enzyme-linked immunosorbent assay testing to facilitate early diagnosis and treatment of toxocariasis.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.022
Threshold uncertainty score0.044

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.001
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0010.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.014
GPT teacher head0.307
Teacher spread0.293 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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