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Record W4416721675 · doi:10.1038/s41533-025-00461-7

Characterizing adult asthma: a cross-sectional epidemiologic study from the canadian primary care sentinel surveillance network

2025· article· en· W4416721675 on OpenAlexafffundabout
Sabrina Allarakhia, Alison Morra, Rebecca Theal, Max Moloney, Samir Gupta, Teresa To, Geneviève C. Digby, David Barber, John Queenan, M. Diane Lougheed

Bibliographic record

Venuenpj Primary Care Respiratory Medicine · 2025
Typearticle
Languageen
FieldMedicine
TopicAsthma and respiratory diseases
Canadian institutionsInstitute for Clinical Evaluative SciencesSickKids FoundationUniversity of TorontoOntario Stroke NetworkQueen's UniversityPublic Health OntarioHospital for Sick ChildrenKingston Health Sciences CentreKingston General HospitalSt. Michael's Hospital
FundersGovernment of Ontario
KeywordsAsthmaComorbidityEpidemiologyMedical prescriptionPrimary careDemographicsAsthma medicationMedical recordHealth care

Abstract

fetched live from OpenAlex

National asthma prevalence data in Canada typically come from health surveys or administrative records. Since most asthma care is provided by family physicians, primary care electronic medical records (EMRs) may offer valuable insights into asthma epidemiology and treatment patterns. This study aimed to estimate the prevalence of adult asthma across Canada using national EMR data, examine the demographics and comorbidities of asthma patients, and review national prescribing practices. We used a validated EMR case definition for adult asthma applied to the Canadian Primary Care Sentinel Surveillance Network (CPCSSN) database, which includes data from 12 networks across Canada. We identified patients with at least one encounter in a two-year period and estimated asthma prevalence, stratified by age, sex, and BMI. Comorbidity rates and medication prescriptions were assessed in patients with asthma. Among 854,567 adults, 94,410 were identified with confirmed/suspected asthma (11% prevalence). Asthma was more common in females (12 vs. 10%, p < 0.0001), across all age brackets except 18-29 years old. A chi-square test for trend showed a decrease in prevalence with increasing age (p < 0.0001). Females with asthma had a higher prevalence of ≥4 comorbidities than males (33 vs. 30%, p < 0.0001). Additionally, 13% of asthma patients were prescribed only as-needed short-acting bronchodilators, without a controller. The 11% asthma prevalence found in this study aligns with national survey estimates, providing support for the use of EMRs in disease and practice surveillance. Future efforts should focus on integrating tools within EMR to support asthma diagnosis and treatment adherence.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow), Science and technology studies
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.110
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.001
Science and technology studies0.0010.001
Scholarly communication0.0000.000
Open science0.0010.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.024
GPT teacher head0.306
Teacher spread0.282 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2025
Admission routes3
Has abstractyes

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