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Record W4416767030 · doi:10.4103/aihb.aihb_175_25

Antibiotic Shortages among Public Sector Hospitals Across Sub-Saharan Africa: A Protocol for an Electronic Survey to Gain Understanding

2025· article· en· W4416767030 on OpenAlexaff
Mukhethwa Munzhedzi, Audrey Chigome, Nenad Miljković, Catrin E. Moore, Stephen Campbell, Brian Godman, Johanna C. Meyer

Bibliographic record

VenueAdvances in Human Biology · 2025
Typearticle
Languageen
FieldImmunology and Microbiology
TopicAntibiotic Use and Resistance
Canadian institutionsInstitute of Infection and Immunity
Fundersnot available
KeywordsAntimicrobial stewardshipDescriptive statisticsPublic healthEconomic shortagePublic sectorHealth careProtocol (science)Descriptive researchWorkflow

Abstract

fetched live from OpenAlex

Background: Antibiotic shortages in public hospitals across sub-Saharan Africa represent a growing public health crisis, increasing antimicrobial resistance (AMR). While European countries have conducted several surveys on medicine shortages, similar data are scarce in sub-Saharan Africa. Ensuring the availability of critical antibiotics among hospitals across Africa is essential for effective treatment of infectious diseases and for implementing targeted Antimicrobial Stewardship Programmes (ASPs) to reduce AMR. Objective: To evaluate the scope, causes and potential solutions regarding antibiotic shortages in public sector hospitals across sub-Saharan Africa. Subsequently, use the findings to make recommendations for future strategies, including ASPs. Methods: A cross-sectional descriptive survey will be undertaken among hospital pharmacists, nurses, physicians and other healthcare professionals across sub-Saharan Africa. An electronic questionnaire, based on the European Association of Hospital Pharmacists (EAHP) model and available in English, French and Portuguese, will gather data on the frequency, types, causes and proposed solutions to antibiotic shortages in hospitals. The survey will run for two months, leveraging existing professional networks to enhance participation. Open-ended responses will be summarised in in Excel. Descriptive statistics will include frequencies, percentages, means and standard deviations, and will be calculated using STATA ® to summarise both categorical and continuous variables. Discussion and Conclusion: This study will provide comprehensive data on the prevalence and drivers of antibiotic shortages in public hospitals in this important region. The findings will inform national and regional health policies, strengthen supply chain resilience and support ASP implementation. This will be the first time that such a comprehensive survey will be conducted across sub-Saharan Africa as part of the drive to reduce AMR.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.191
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.001
Scholarly communication0.0000.000
Open science0.0010.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.054
GPT teacher head0.370
Teacher spread0.316 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes1
Has abstractyes

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