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Record W4416771391 · doi:10.3389/jaws.2025.15452

A Narrative Review of Mesh Suture in Abdominal Wall Reconstruction: Biomechanics, Early Outcomes, and Proposed Clinical Algorithm

2025· review· en· W4416771391 on OpenAlexaff
Megan M. Perez, Gregory A. Dumanian, Paige N. Hackenberger, David A. Ross, Jonah J. Stulberg, Michael B. Shapiro

Bibliographic record

VenueJournal of Abdominal Wall Surgery · 2025
Typereview
Languageen
FieldMedicine
TopicHernia repair and management
Canadian institutionsSt. Thomas HospitalWestern University
Fundersnot available
KeywordsAbdominal wallNarrative reviewFibrous jointSurgical meshRandomized controlled trialCurrent (fluid)

Abstract

fetched live from OpenAlex

Background: Suture repair of abdominal wall defects is prone to failure due to suture pull-through. In contrast, planar mesh reinforcement improves durability but is limited by increased foreign body burden, need for additional tissue dissection, and challenges in contaminated fields. Mesh suture offers a potential alternative combining both the ease of suture repair with improved load distribution and early tissue integration, characteristics of planar mesh repairs. This review summarizes the biomechanical rationale, histologic characteristics, and early clinical experiences with mesh suture to date. Methods: A narrative review of preclinical and clinical literature regarding mesh suture was performed using a targeted search of PubMed and Google Scholar with key terms ("mesh suture" or "Duramesh"). Studies were included if they evaluated mesh suture in biomechanical, preclinical or clinical contexts. A proposed clinical algorithm based on institutional experiences is presented to illustrate patient selection and technique. Results: Preclinical studies demonstrate favorable mechanical performance and early fibrovascular incorporation. Early clinical data from registries and institutional cohorts suggests mesh suture is feasible even in contaminated settings with outcomes that compare to both standard suture and planar mesh repairs. Conclusion: Mesh suture may offer a reinforcement strategy that balances mechanical support with tissue preservation in abdominal wall reconstruction. Current clinical evidence remains preliminary, and additional prospective, randomized studies are needed to more definitely evaluate its clinical performance over time.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.007
metaresearch head score (Gemma)0.002
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Other design · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.871
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0070.002
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0080.003
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0010.002
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.042
GPT teacher head0.379
Teacher spread0.337 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designOther design
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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