U.S. public perceptions on whether risk of dementia and stroke can be modified through maintaining or changing lifestyle
Bibliographic record
Abstract
BACKGROUND: Epidemiological studies suggest that approximately 40% of dementia and 60% of stroke cases could be prevented through adequate control of modifiable risk factors. Limited data are available on the public perceptions in the United States (U.S.) on whether the risk of dementia and stroke can be modified through lifestyle changes. METHODS: A survey utilizing questions from validated questionnaires was distributed to a sample of the general U.S. POPULATION: We performed multivariable logistic regression analyses for which the binary exposure was ever having known someone with dementia or stroke, and the primary outcomes were the perceptions on whether dementia and stroke risk could be modified through maintaining or changing lifestyle. RESULTS: We included 1,478 participants (mean [SD] age: 45.5 [15.9], 51.1% female), of whom 80% (N = 1185) ever knew someone with dementia or stroke. Over 75% of all participants perceived that a healthy lifestyle can lower dementia and stroke risks. Following multivariable analyses, participants who ever knew someone with dementia or stroke were more likely to agree that maintaining (adjusted Odds Ratio [aOR] = 1.41, 95%CI:1. 10-1.96) and that changing lifestyle (aOR = 1.59, 95%CI:1.14-2.24) reduces dementia risk, when adjusted for age, sex assigned at birth, race/ethnicity, level of education, employment status, and being a caregiver for someone with dementia or stroke. Participants who knew someone with dementia or stroke were also more likely to agree that maintaining (aOR = 1.77, 95%CI:1.27-2.47) or changing lifestyle (aOR = 2.31, 95%CI:1.41-3.76) reduces stroke risk when adjusted for similar confounders. DISCUSSION: This cross-sectional cohort, mimicking the general U.S. population, demonstrated that over 80% of individuals ever knew someone with dementia or stroke and that this was positively associated with the perceptions that dementia and stroke risk could be modified through lifestyle changes. The widespread exposure of the U.S. public to dementia and stroke first-hand can be leveraged into more effective preventive strategies.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.002 | 0.006 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.001 | 0.001 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.001 | 0.001 |
| Open science | 0.000 | 0.001 |
| Research integrity | 0.000 | 0.001 |
| Insufficient payload (model declined to judge) | 0.004 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".