Primary Eosinophilic Colitis Manifesting As Acute Appendicitis: A Case Report and Literature Review
Bibliographic record
Abstract
Eosinophilic colitis (EC) is a rare inflammatory disorder characterised by eosinophilic infiltration of the gastrointestinal tract, often resulting in varied clinical presentations. The role of the appendix in such inflammatory processes remains underexplored. We describe the case of a 48-year-old male who presented with acute abdominal pain, initially managed as uncomplicated appendicitis. He had a history of chronic diarrhoea and no atopic background. Histological examination of the resected appendix revealed eosinophilic infiltration without evidence of acute inflammation. Subsequent investigations ruled out secondary causes, leading to a diagnosis of primary EC. This case highlights the potential for eosinophilic appendicitis to mimic acute appendicitis clinically and the need for postoperative evaluation to exclude systemic eosinophilic gastrointestinal disorders. This represents, to our knowledge, a case of primary EC resolving after appendicectomy. We hypothesise that the appendix played a contributory role in the maintenance of chronic mucosal inflammation in this patient.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.001 |
| Meta-epidemiology (narrow) | 0.001 | 0.001 |
| Meta-epidemiology (broad) | 0.001 | 0.001 |
| Bibliometrics | 0.008 | 0.006 |
| Science and technology studies | 0.001 | 0.002 |
| Scholarly communication | 0.002 | 0.003 |
| Open science | 0.001 | 0.001 |
| Research integrity | 0.002 | 0.001 |
| Insufficient payload (model declined to judge) | 0.003 | 0.002 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".