Isolated goat and sheep milk allergy in an adult in the absence of bovine sensitization
Bibliographic record
Abstract
Cow's milk (CM) allergy is the most common food allergy in children, with cross-reactivity to goat and sheep milk (GSM) representing a common outcome due to high protein homology. However, isolated GSM allergy in CM-tolerant individuals is rare and poorly documented in the literature. We describe a 27-year-old male of Mediterranean origin who experienced two episodes of anaphylaxis after consuming sheep and goat cheese, despite regular CM consumption. Skin prick testing confirmed sensitization to GSM but not CM. This report contributes to the growing evidence of adult-onset isolated GSM allergy. Isolated GSM allergy typically presents later in life and may be underrecognized due to limited clinical awareness. We review the potential for species-specific mammalian milk protein allergy, likely mediated by structural differences in casein proteins. Clinicians should be cognisant to consider GSM sensitization in patients presenting with allergic reactions to dairy products, especially in multicultural populations with increasing GSM dietary exposure.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.001 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.001 | 0.001 |
| Insufficient payload (model declined to judge) | 0.002 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".