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Record W4416877316 · doi:10.1681/asn.2025ybsvhfg9

Person-Centered Integrated Care for Mild to Moderate CKD and Multimorbidity: A Scoping Review

2025· review· en· W4416877316 on OpenAlexaff
Jennifer A. Brown, Sabrina Jassemi, Taylor Hecker, Nicole McKenzie, Gillian Crysdale, Nicholle Zym, Meghan J. Elliott, Aminu K. Bello, Brenda R. Hemmelgarn, Kerry McBrien, Maria Santana, Nancy Verdin, Maoliosa Donald

Bibliographic record

VenueJournal of the American Society of Nephrology · 2025
Typereview
Languageen
FieldMedicine
TopicChronic Disease Management Strategies
Canadian institutionsUniversity of AlbertaUniversity of Calgary
Fundersnot available
KeywordsIntegrated careKidney diseaseMEDLINEHealth carePatient care

Abstract

fetched live from OpenAlex

Background: Chronic kidney disease (CKD) is increasing in prevalence and most patients with this condition also experience multimorbidity, defined as two or more co-existing chronic health conditions, with recent reviews suggesting this includes up to 99% of CKD patients. Care and management for these patients is complex and multifaceted. Person-centered integrated care (PC-IC) is an ideal approach to support this population, but evidence for developing and implementing PC-IC strategies for patients with mild to moderate CKD is currently lacking. Methods: We conducted this review in accordance with the JBI methodology for scoping reviews and used the PRISMA-ScR. We searched for publications and grey literature that discuss the care of adult patients with mild to moderate chronic kidney disease experiencing multimorbidity, who may be the beneficiaries of PC-IC strategies. The Rainbow Model of Integrated Care is a framework for different levels of integrated care interventions, including macro- (system), meso- (organizational and professional), and micro-levels (clinical), all of which were considered in this review. Results: Our search of published works collected 31812 entries. From this, 721 papers progressed to full text screening. We included 136 for data extraction which is ongoing. Our grey literature search yielded one paper. General themes for integrated care strategies implemented that were revealed in our search include: - Collaborative care between nephrology and other medical specialities - Collaborative care between nephrology and other allied healthcare professions - Pharmacist initiated medication education and titration - Health knowledge education interventions delivered by nurses - Self-management education - Streamlined referrals between nephrology and primary care - Electronic health record applications - “Tele-nephrology” Conclusion: Our diverse research team is in the process of completing data extraction with the goal of better understanding the breadth of evidence that exists for PC-IC in multi-morbid patients with CKD. With this information, we hope to create well developed, and patient centered models of care for this increasingly complex and diverse population. Funding: Government Support – Non-U.S.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.015
metaresearch head score (Gemma)0.068
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Systematic review · Consensus signal: Systematic review
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.016
Threshold uncertainty score0.077

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0150.068
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0050.007
Bibliometrics0.0160.018
Science and technology studies0.0010.001
Scholarly communication0.0050.004
Open science0.0030.003
Research integrity0.0030.002
Insufficient payload (model declined to judge)0.0060.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.120
GPT teacher head0.414
Teacher spread0.294 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designSystematic review
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

Explore more

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