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Record W4416912159 · doi:10.1021/jasms.5c00303

A Radio Frequency Ion Guide for Transporting Cooled Ions Through Differential Vacuum Stages: Design and Simulation

2025· article· en· W4416912159 on OpenAlexaff
Bingyin Xu, Weimin Wang, Huanming Wu, Jianfeng Chen, Fuzhong Ni, Dongdong Zhou, Li Ding

Bibliographic record

VenueJournal of the American Society for Mass Spectrometry · 2025
Typearticle
Languageen
FieldChemistry
TopicMass Spectrometry Techniques and Applications
Canadian institutionsIONICS Mass Spectrometry (Canada)
Funders3315 Innovation Team in Ningbo CityNational Key Research and Development Program of China
KeywordsIonAperture (computer memory)VoltageQuadrupoleRadio frequencyTransmission (telecommunications)PlanarRadio-frequency quadrupoleAnalytical Chemistry (journal)

Abstract

fetched live from OpenAlex

In order to transport ions from an intermediate-pressure collisional cooling device to a planar electrostatic ion trap (PEIT) mass analyzer in an ultrahigh-vacuum chamber, a segmented radio frequency (RF) quadrupole system was designed and investigated by using an ion optical simulation. Two gas-flow-limiting units were employed in the system, allowing the differential pumping to establish a pressure difference of 7 orders of magnitude. Flow-limiting units including a plain aperture lens and 3 small quadrupoles in different shapes were investigated, and the transmission efficiency and energy distribution of the transported ions were evaluated. The small quadrupoles with conical front-ends inserted between the multiple segments gave the best transmission efficiency, and the collisional cooled ions can maintain their low energy distribution after being transported to the ultrahigh-vacuum stage. With an RF voltage amplitude of 200 V, the maximum transmission efficiency reached above 90%. After ions are cooled in the high-pressure quadrupole segment, the extraction voltage difference in high-pressure region needs to be low enough to avoid reheating the ions during the transport. It was found that an extraction voltage difference below 1.2 V can restrict the half width of the energy spread within 0.5 eV, which is required by PEIT to get ultrahigh mass resolution.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Simulation or modeling · Consensus signal: Simulation or modeling
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.003
Threshold uncertainty score0.010

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0010.000
Research integrity0.0010.000
Insufficient payload (model declined to judge)0.0030.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.018
GPT teacher head0.309
Teacher spread0.291 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designSimulation or modeling
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes1
Has abstractyes

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Same venueJournal of the American Society for Mass SpectrometrySame topicMass Spectrometry Techniques and ApplicationsFrench-language works237,207