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Record W4416959727 · doi:10.1136/bmjopen-2025-105517

Influence of the COVID-19 pandemic on drug and healthcare utilisation among First Nations with diabetes in Alberta, Canada: a retrospective cohort study

2025· article· en· W4416959727 on OpenAlexafffundabout
Olivia Weaver, Chris Sarin, Salim Samanani, Lynden Crowshoe, Ming Ye, Dean T. Eurich

Bibliographic record

VenueBMJ Open · 2025
Typearticle
Languageen
FieldSocial Sciences
TopicIndigenous Health, Education, and Rights
Canadian institutionsUniversity of CalgaryAlberta HealthUniversity of Alberta
FundersDiabetes Canada
KeywordsPandemicRetrospective cohort studyHealth carePublic healthEpidemiologyDiabetes mellitusCohort studyDrugMEDLINE

Abstract

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OBJECTIVES: The purpose of this study was to assess changes in diabetes management and healthcare utilisation among First Nations with diabetes in Alberta before and during the COVID-19 pandemic. DESIGN: This analysis used a retrospective cohort in a case-control design. Individual-level administrative health datasets (1 April 2018 to 31 March 2022) were linked and data were formatted as a segmented interrupted time series. SETTING: This study took place in Alberta, Canada using administrative data. PARTICIPANTS: Adult First Nations and non-First Nations (matched 1:1) with diabetes and living in Alberta were included (n=28 101; 53% female, 47% male). PRIMARY AND SECONDARY OUTCOME MEASURES: The primary outcome was the change in incidence rate of general practitioner (GP) visits, emergency department (ED) visits, hospitalisations and diabetes-related drug dispenses during-COVID-19 versus pre-COVID-19, quantified using generalised linear regressions. The secondary outcome was to report the reasons for non-drug outcomes pre-COVID-19 and during-COVID-19, based on primary diagnosis International Statistical Classification of Diseases and Related Health Problems codes. RESULTS: Pre-COVID-19, baseline rates of GP visits, ED visits, hospitalisations and drug dispenses were significantly higher among First Nations compared with non-First Nations (rate differences 398.32 (391.97-404.67), 100.58 (98.32-102.84), 14.49 (13.56-15.43), 876.98 (868.72-885.24) per 100 person-years (PY); p<0.0001). This corresponds to rates greater by 33%, 78%, 62% and 45%, respectively (p<0.0001). These disparities generally became greater during COVID-19 (rate differences 437.21 (430.83-443.59), 91.29 (89.28-93.31), 16.90 (16.00-17.80), 1066.55 (1057.74-1075.37) per 100 PY; p<0.0001) and rates higher by 36%, 95%, 86% and 49%, respectively (p<0.0001). Among First Nations during COVID-19, the rate of ED visits and hospitalisations decreased from baseline by 17% and 2%; the rate of GP visits and drug dispenses increased by 0.54% and 15%. Non-First Nations experienced greater comparative drops in GP visits, ED visits and hospitalisations, and a smaller increase in drug dispenses. There were no discernible patterns regarding the secondary outcome. CONCLUSIONS: Healthcare utilisation was substantially elevated among First Nations compared with non-First Nations peoples before and during COVID-19. While the generalisability of our findings to other health systems and populations may be limited, our findings are clinically applicable among First Nations across Alberta in order to help direct public health programming post-COVID-19.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.025
Threshold uncertainty score0.104

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0020.002
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0000.001
Bibliometrics0.0020.004
Science and technology studies0.0020.001
Scholarly communication0.0020.000
Open science0.0010.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.024
GPT teacher head0.359
Teacher spread0.335 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes3
Has abstractyes

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