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UA-UNet: Uncertainty Aware Pseudo-Label Generation in Residual U-Net for Medical Image Segmentation

2025· article· en· W4416960425 on OpenAlexaff
Seyed Sina Ziaee, Farhad Maleki, Katie Ovens

Bibliographic record

Venuenot available
Typearticle
Languageen
FieldComputer Science
TopicAdvanced Neural Network Applications
Canadian institutionsUniversity of Calgary
Fundersnot available
KeywordsInterpretabilitySegmentationImage segmentationScale-space segmentationConsistency (knowledge bases)ResidualPattern recognition (psychology)Noise (video)Dice

Abstract

fetched live from OpenAlex

Medical image segmentation is crucial for accurate diagnosis and treatment planning. Most segmentation models are developed through supervised learning, which requires access to large amounts of annotated data. However, acquiring such datasets is often expensive and time-consuming. Semi-supervised learning (SSL) approaches alleviate this challenge by leveraging both labeled and unlabeled data to improve model performance. While SSL methods have achieved promising results, they still have some limitations. Predictions made by these methods disregard the model uncertainty, leading to unreliable predictions. The predictions made by these models are often affected by the noise introduced during the SSL process. Additionally, these models fail to adapt well to complex medical images and are unable to scale well in out-of-domain samples. To address these limitations, we propose UA-UNet, an uncertainty-guided teacher-student model architecture built on top of the Residual U-Net for multi-class medical image segmentation. The model incorporates uncertainty estimation, which guides the generation of high-quality pseudo-labels from an ensemble of teacher models. By combining consistency regularization and pseudo-labeling, our method effectively reduces the influence of high-uncertainty regions while enhancing segmentation accuracy. We compared the model with 10 other methods on the 2023 Kidney Tumor Segmentation Challenge dataset (KiTS23). The proposed approach outperformed state-of-the-art models with a Dice score of 0.901 and IoU of 0.891. The proposed model also provides uncertainty maps, which could enhance the interpretability of the segmentation result. These features make UA-UNet a robust method for semi-supervised segmentation in medical imaging, particularly when labeled data is scarce.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Simulation or modeling · Consensus signal: none
GenreCandidate signal: Methods · Consensus signal: Methods
Teacher disagreement score0.953
Threshold uncertainty score0.429

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.024
GPT teacher head0.332
Teacher spread0.309 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designSimulation or modeling
Domainnot available
GenreMethods

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations0
Published2025
Admission routes1
Has abstractyes

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