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Developmental Differences in Hippocampal EEG During REM Sleep: A Chaotic and Spectral Analysis

2025· article· W4416963662 on OpenAlexaff
Liu Neptali Restrepo Sanabria, Chris Pham, Taikang Ning

Bibliographic record

Venuenot available
Typearticle
Language
FieldNeuroscience
TopicSleep and Wakefulness Research
Canadian institutionsTrinity College
Fundersnot available
KeywordsHippocampal formationCorrelation dimensionChaoticElectroencephalographySpectral analysisDentate gyrusNonlinear systemDynamics (music)

Abstract

fetched live from OpenAlex

This study examines developmental differences in the hippocampal electroencephalogram (EEG) during rapid eye movement (REM) sleep in rats, with a focus on characterizing the underlying nonlinear dynamics using an RMS-normalized modified Grassberger-Procaccia (G-P) algorithm. EEG signals were recorded from two key hippocampal subfields, the CA1 region and the dentate gyrus (DG), in freely moving animals at two postnatal stages: 15 and 90 days of age. To quantify the complexity of the EEG, we employed time-delay embedding and calculated the correlation dimension via a modified GP method. The reconstructed phase space trajectories revealed age-dependent differences in the dimensional complexity of the signals. Specifically, younger animals exhibited significantly greater correlation dimension values in the DG relative to CA1, a difference that was no longer present in older animals. These findings suggest that the maturation of hippocampal circuits during early development is accompanied by changes in the structure of chaotic neural activity during REM sleep. Methodologically, we apply an RMS-normalized variant of the Grassberger-Procaccia algorithm to stabilize$D_{2}$across embeddings, enabling the first subfield-by-age comparison of nonlinear REM EEG dynamics in early development. Our results underscore the utility of chaotic signal analysis in probing subtle developmental dynamics not readily captured by conventional linear techniques.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.001
Threshold uncertainty score0.002

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.028
GPT teacher head0.282
Teacher spread0.254 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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