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Record W4416992434 · doi:10.1038/s41746-025-02187-9

Predicting 1-year successful clinical use of an arteriovenous access for hemodialysis using machine learning

2025· article· en· W4416992434 on OpenAlexafffund
Ben Li, Naomi Eisenberg, Derek Beaton, Douglas S. Lee, Leen Al‐Omran, Duminda N. Wijeysundera, Mohamad A. Hussain, Ori D. Rotstein, Elisa Greco, Charles de Mestral, Muhammad Mamdani, Graham Roche‐Nagle, Mohammed Al-Omran

Bibliographic record

Venuenpj Digital Medicine · 2025
Typearticle
Languageen
FieldHealth Professions
TopicCentral Venous Catheters and Hemodialysis
Canadian institutionsOntario Medical AssociationUniversity Health NetworkArtificial Intelligence in Medicine (Canada)University of TorontoSt. Michael's Hospital
FundersCanadian Institutes of Health ResearchPhysicians' Services Incorporated FoundationBrigham and Women's HospitalUniversity of TorontoMinistry of Health, Ontario
KeywordsLogistic regressionVascular accessHemodialysisClinical PracticeHemodialysis accessQuality (philosophy)Predictive modelling

Abstract

fetched live from OpenAlex

Arteriovenous (AV) access is important to support long-term hemodialysis; however, a significant proportion fail due to inadequate maturation or other complications. Tools that can predict long-term AV access success may guide clinical decision-making but remain limited. We developed machine learning (ML) algorithms that predict 1-year successful clinical use of an AV access using pre-operative data. The Vascular Quality Initiative (VQI) was used to identify patients who underwent surgical AV fistula/graft creation between 2011-2024. We identified 111 pre-operative demographic, clinical, and anatomic features. Six ML models were trained with 10-fold cross-validation. Overall, 59,674 patients underwent AV access creation and 28,304 (47.4%) had 1-year successful clinical use of their index AV access. The best prediction model was XGBoost, achieving an AUROC of 0.90. In comparison, logistic regression had an AUROC of 0.70. The XGBoost model accurately predicted 1-year successful clinical use of an AV access for hemodialysis, performing better than logistic regression.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.003
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.632
Threshold uncertainty score0.753

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.003
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.001
Science and technology studies0.0010.000
Scholarly communication0.0000.001
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.137
GPT teacher head0.459
Teacher spread0.322 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2025
Admission routes2
Has abstractyes

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