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Record W4417018654 · doi:10.1111/dar.70067

Understanding Gender Differences in Injecting‐Related Harms Among an Australian Sample of People Who Inject Drugs

2025· article· en· W4417018654 on OpenAlexaff
Daisy Gibbs, Rachel Sutherland, Sarah Larney, Lucy Thi Tran, Amanda Roxburgh, Raimondo Bruno, Samantha Colledge‐Frisby

Bibliographic record

VenueDrug and Alcohol Review · 2025
Typearticle
Languageen
FieldMedicine
TopicHIV, Drug Use, Sexual Risk
Canadian institutionsCentre Hospitalier de l’Université de Montréal
FundersNational Health and Medical Research CouncilSeqirusDepartment of Health and Aged Care, Australian GovernmentIndivior
KeywordsPsychological interventionSample (material)Significant differenceHarm reduction

Abstract

fetched live from OpenAlex

INTRODUCTION: People who inject drugs may experience several non-viral injecting-related injuries and diseases (IRID), including skin and soft tissue infection (SSTI) and venous disease, often resulting from bacteria introduced via unsafe injecting practices or environments. Women are overrepresented among those reporting multiple and recent IRID. However, limited evidence exists about how gender interacts with known IRID risk factors. METHODS: Surveys were conducted 2009-2023 with approximately 900 Australians who inject drugs per year (N = 7538 total). Participants self-reported past-month drug use behaviours and IRID experience. We conducted multivariable binary logistic regression to determine the relationship between gender and SSTI and venous disease. To examine whether gender uniquely affected specific injecting risk behaviours with respect to SSTI and venous disease, two interaction terms were separately added: (i) gender and injecting frequency; (ii) gender and reuse of one's needles. RESULTS: Surveys were completed by 5038 men and 2500 women. Past-month SSTI was reported by 8% of the sample (95% confidence interval 7%-9%), with a higher proportion among women (10%) than men (7%). Overall, 4% reported past-month venous disease (95% confidence interval 3%-4%), a higher proportion among women (5%) than men (3%). Examining both outcomes, no statistically significant interactions between gender and needle reuse or injecting frequency were found. DISCUSSION AND CONCLUSIONS: Despite no statistically significant interaction between gender and reuse or injecting frequency, our study demonstrates a gender difference in exposure to risk factors associated with SSTIs and venous disease. Interventions to reduce SSTI and venous disease, particularly those deemed safe and appropriate by women, are needed.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.119
Threshold uncertainty score0.856

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.159
GPT teacher head0.384
Teacher spread0.225 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes1
Has abstractyes

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