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Record W4417048151 · doi:10.1016/j.cjco.2025.11.020

Use of Intravascular Imaging to Guide Percutaneous Coronary Interventions: Experience from a Single, High-Volume Canadian Centre

2025· article· en· W4417048151 on OpenAlexaffabout
Mehdi Madanchi, Natalia Pinilla‐Echeverri, Shamir R Mehta, Jon-David Schwalm, Nicholas Valettas, James L. Velianou, Micheal Tsang, Madhu K. Natarajan, Sanjit S. Jolly, Tej Sheth, Matthew Sibbald

Bibliographic record

VenueCJC Open · 2025
Typearticle
Languageen
FieldMedicine
TopicCoronary Interventions and Diagnostics
Canadian institutionsHamilton Health SciencesMcMaster UniversityPopulation Health Research Institute
FundersAbbott VascularAmgenSchweizerischer Nationalfonds zur Förderung der Wissenschaftlichen ForschungNational Science Foundation
KeywordsPercutaneousPercutaneous coronary interventionMedical imagingCoronary artery diseaseIntravascular ultrasoundCoronary angiography

Abstract

fetched live from OpenAlex

Background Intravascular imaging (IVI) improves outcomes in complex percutaneous coronary intervention (PCI) and is recommended by the latest guidelines. However, data about its real-world application remains limited. Methods We conducted a retrospective audit of 300 consecutive PCI cases. Lesions were classified as complex if they involved >1 following characteristics: bifurcation, severe calcifications, CTO, long lesions, ostial location and involvement of the LM. IVI use was analyzed by lesion subtype and individual operator. Results Of 300 consecutive PCI cases, 146 (49%) were classified as complex PCI. IVI was used in 53% of complex PCIs and 23% of noncomplex PCIs. Among patients undergoing complex PCI, IVI was most frequently performed in CTOs (86%) and LM (76%), but its use remained below 50% for bifurcations, severe calcified and long lesions. IVI-guided PCI was associated with higher contrast use (215 ± 78 mL vs. 179 ± 65 mL, P=0.003) and longer procedural duration (72 ± 32 minutes vs. 51 ± 22 minutes, P < 0.001) and varied widely across operators, ranging from 0-79% in the overall population (p<0.001) to 0-90% in complex lesions (p=0.004). Notably, IVI adoption declined with increasing operator age (OR 0.88 per +1 year; 95% CI 0.78–0.98), whereas it increased with lesion complexity (OR 2.34 per additional complexity feature; 95% CI 1 1.62–3.39). Conclusions Despite current evidence and guideline recommendations, IVI use showed notable variation across operators. Standardizing IVI utilization through education, protocols, and system-level support will be essential to promote guideline-concordant practice.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesInsufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.276
Threshold uncertainty score0.998

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0030.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.032
GPT teacher head0.315
Teacher spread0.284 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designNot applicable
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes2
Has abstractyes

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