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Record W4417102728 · doi:10.3389/fnagi.2025.1663237

Cognitive impairment and dependency in activities of daily living: a cross-lagged analysis

2025· article· en· W4417102728 on OpenAlexaboutno aff
Xuewei Fu, Shuming Ji, Jiafeng Li, Ting Chen, Weihong Kuang

Bibliographic record

VenueFrontiers in Aging Neuroscience · 2025
Typearticle
Languageen
FieldMedicine
TopicDementia and Cognitive Impairment Research
Canadian institutionsnot available
Fundersnot available
KeywordsCognitionCognitive impairmentDependency (UML)Activities of daily livingAssociation (psychology)Psychological interventionCognitive decline

Abstract

fetched live from OpenAlex

Background: This study investigates the bidirectional relationship between cognitive function and Activities of Daily Living (ADL) at varying levels of cognitive impairment. Specifically, it explores how cognitive function affects Basic Activities of Daily Living (BADL) and Instrumental Activities of Daily Living (IADL) over time, and how changes in ADL impact cognitive function. Method: A retrospective analysis of clinical data was conducted using cross-lagged panel models to examine the relationships between cognitive function and ADL. Cognitive function was measured using the Montreal Cognitive Assessment, while ADL were assessed via standardized measures of both BADL and IADL at two time points. Participants were grouped according to the severity of their initial cognitive impairment, allowing for comparative analysis across different levels of impairment. Results: < 0.001). Subgroup analyses indicated that these associations were most pronounced in individuals with moderate cognitive impairment. Conclusion: This study highlights the significant association between cognitive function and ADL, with lower baseline cognitive function predicting increased dependency, particularly in IADL. The findings emphasize the importance of early cognitive health interventions to prevent further decline in daily functioning, especially in individuals with moderate cognitive impairment.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.005
metaresearch head score (Gemma)0.005
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.014
Threshold uncertainty score0.027

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0050.005
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.001
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0010.000
Open science0.0010.001
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0030.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.014
GPT teacher head0.332
Teacher spread0.318 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

Explore more

Same venueFrontiers in Aging NeuroscienceSame topicDementia and Cognitive Impairment ResearchFrench-language works237,207