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Record W4417127228 · doi:10.1159/000549556

Combined Renuvion and Endolift Therapy Suggests Enhanced Skin Tightening Compared to Monotherapy in Upper Arm Rejuvenation: A Case Report

2025· article· en· W4417127228 on OpenAlexaff
Mohammadali Nilforoushzadeh, Tannaz Fakhim, Seyedeh Nasim Mirbahari, Mohammad Hasan Shahverdi, Rozhin Enamzadeh

Bibliographic record

VenueCase Reports in Dermatology · 2025
Typearticle
Languageen
FieldMedicine
TopicDermatologic Treatments and Research
Canadian institutionsMcMaster University
Fundersnot available
KeywordsSoft tissueCompression therapyForearmBiomechanics

Abstract

fetched live from OpenAlex

Introduction: Skin laxity, a common esthetic concern, drives demand for non-surgical solutions. Energy-based devices like Renuvion® (helium plasma/radiofrequency) and Endolift® (1,470 nm diode laser) offer minimally invasive tightening, yet their combined efficacy remains underexplored. This study evaluates synergistic effects of Renuvion® and Endolift® through an intra-patient comparison. Case Presentation: A 44-year-old female with moderate upper arm laxity underwent Renuvion® alone on the right arm and combined Renuvion® + Endolift® on the left. Endolift® (6 W, 50 ms ON/OFF pulses, 600 μm fiber) delivered 4,000 J–5,000 J per arm via subdermal scraping. Renuvion® followed 1 week later, using standard subdermal settings. Outcomes were assessed via laxity scoring, circumferential measurements, blinded practitioner evaluations, and patient feedback at 8 weeks. The combination arm demonstrated a higher reduction in circumference (34.3% vs. 28.8%) and superior practitioner ratings (3/3 vs. 2/3), indicating enhanced skin tightening. Blinded practitioners rated the left arm’s improvement as “marked” (score 3/3) vs. “moderate” (score 2/3) for the right. Patient satisfaction aligned with objective metrics, citing the left arm as “tighter” and “more contoured.” No adverse events occurred. Conclusion: Combining Renuvion® and Endolift® enhanced skin tightening compared to Renuvion® monotherapy, which may suggest synergistic subdermal remodeling. This dual-modality approach may optimize outcomes in fibrous anatomical regions, though larger controlled studies are warranted.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Case report · Consensus signal: Case report
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.085
Threshold uncertainty score0.840

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.021
GPT teacher head0.350
Teacher spread0.329 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designCase report
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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