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Record W4417152952 · doi:10.1093/ehjci/jeaf348

Current and future use of artificial intelligence in valvular heart disease imaging

2025· article· en· W4417152952 on OpenAlexafffund
Partho P. Sengupta, Timothy J. Poterucha, Théo Pezel, Teresa S.M. Tsang, Bernard Cosyns

Bibliographic record

VenueEuropean Heart Journal - Cardiovascular Imaging · 2025
Typearticle
Languageen
FieldMedicine
TopicCardiac Valve Diseases and Treatments
Canadian institutionsVancouver General HospitalUniversity of British ColumbiaArtificial Intelligence in Medicine (Canada)
FundersTakeda CanadaBristol-Myers Squibb CanadaButterfly FoundationServierSiemens HealthineersUniversity of British ColumbiaGenome British ColumbiaBayer FundGenome CanadaGeneral ElectricBaxter InternationalInstitut de Cardiologie de MontréalMayo ClinicBayerNational Institutes of HealthAstraZeneca EspañaAbbott LaboratoriesJanssen BiotechCanadian Institutes of Health ResearchNational Science FoundationAmerican Heart AssociationNational Heart, Lung, and Blood InstitutePfizer
Keywordsvalvular heart diseaseMagnetic resonance imagingMedical imagingCardiac magnetic resonanceIntracardiac injectionCardiac magnetic resonance imagingApplications of artificial intelligenceCardiac imaging

Abstract

fetched live from OpenAlex

Valvular heart disease (VHD) remains significantly underdiagnosed and undertreated. This review examines an artificial intelligence (AI)-enhanced 'spoke-hub-node' care model designed to improve the early detection, risk stratification, and treatment of VHD. In this model, AI tools-such as automated ECG interpretation, digital stethoscopes, and point-of-care ultrasound-facilitate decentralized screening and referral for cardiac imaging at the community level. During the transition from outpatient settings to tertiary care centres, AI-integrated echocardiography, cardiac tomography, and magnetic resonance imaging facilitate advanced diagnostic evaluation and inform procedural planning. We review emerging innovations that can enhance this model of care delivery-including unsupervised machine learning to uncover novel VHD phenotypes, generative AI for automated reporting, the use of digital twins to simulate interventions, and the integration of multiple AI agents to support heart team meetings. These advances are followed by the emerging use of AI in robotic transoesophageal and intracardiac echocardiography, as well as in fusion fluoroscopy imaging, to guide valve interventions. While outlining the challenges inherent in this rapidly evolving field, the review's central contribution is its vision to connect the continuum-from AI-enabled community screening to personalized, image-guided therapies at tertiary care centres-offering a scalable and equitable model for VHD care.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.332
Threshold uncertainty score0.925

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.002
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.027
GPT teacher head0.335
Teacher spread0.307 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations3
Published2025
Admission routes2
Has abstractyes

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