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Record W4417153210

MIMIC-MJX: Neuromechanical Emulation of Animal Behavior.

2025· article· en· W4417153210 on OpenAlexaff
C. Y. Zhang, Yuanjia Yang, Aidan Sirbu, Elliott T. T. Abe, Emil Wärnberg, Eric Leonardis, Diego Aldarondo, Adam J. Lee, Aaditya Prasad, Jason Foat, Kaiwen Bian, Joshua Park, Hutton Saunders, Akira Nagamori, Ayesha Thanawalla, Kee Wui Huang, Fabian Plum, Hendrik Beck, Steven W. Flavell, David Labonte, Blake A. Richards, Bingni W. Brunton, Eiman Azim, Bence P. Ölveczky, Talmo Pereira

Bibliographic record

VenuePubMed · 2025
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicZebrafish Biomedical Research Applications
Canadian institutionsMontreal Neurological Institute and HospitalCanadian Institute for Advanced ResearchMcGill UniversityMila - Quebec Artificial Intelligence Institute
Fundersnot available
KeywordsEmulationKinematicsProcess (computing)Motor controlControl (management)Artificial neural networkControl system
DOInot available

Abstract

fetched live from OpenAlex

The primary output of the nervous system is movement and behavior. While recent advances have democratized pose tracking during complex behavior, kinematic trajectories alone provide only indirect access to the underlying control processes. Here we present MIMIC-MJX, a framework for learning biologically-plausible neural control policies from kinematics. MIMIC-MJX models the generative process of motor control by training neural controllers that learn to actuate biomechanically-realistic body models in physics simulation to reproduce real kinematic trajectories. We demonstrate that our implementation is accurate, fast, data-efficient, and generalizable to diverse animal body models. Policies trained with MIMIC-MJX can be utilized to both analyze neural control strategies and simulate behavioral experiments, illustrating its potential as an integrative modeling framework for neuroscience.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Simulation or modeling · Consensus signal: Simulation or modeling
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.006
Threshold uncertainty score0.021

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.002
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0000.001
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.001
Open science0.0020.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0060.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.020
GPT teacher head0.295
Teacher spread0.275 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designSimulation or modeling
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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Same venuePubMedSame topicZebrafish Biomedical Research ApplicationsFrench-language works237,207