Improved pixel-wise calibration for charge-integrating hybrid pixel detectors with performance validation
Bibliographic record
Abstract
The MÖNCH hybrid pixel detector, with a 25 μ m pixel pitch and fast charge-integrating readout, has demonstrated subpixel resolution capabilities, i.e., particle localization precision below the pixel pitch by exploiting the analog charge readout, for X-ray imaging and deep learning-based electron localization in electron microscopy. Fully exploiting this potential requires extensive calibration to ensure both linearity and uniformity of the pixel response, which is challenging for detectors with a large dynamic range. To overcome the limitations of conventional calibration methods, we developed an accurate and efficient correction method to achieve pixel-wise gain and nonlinearity calibration based on the backside pulsing technique. A three-dimensional lookup table, indexed by pixel X and Y coordinates and value in analog-to-digital units (ADU), was generated for all pixels across the full dynamic range, mapping the pixel response to a calibrated linear energy scale. Compared with conventional linear calibration, the proposed method yields negligible deviations between the calibrated and nominal energies for photons and electrons. The improvement in energy resolution ranges from 4% to 22% for 15–25 keV photons and from 12% to 21% for 60–200 keV electrons. Deep learning-based electron localization demonstrates a 4% improvement in spatial resolution when using the proposed calibration method. This approach further enables rapid diagnosis of the cause of bad pixels and estimation of bump-bonding yield.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.002 | 0.003 |
| Meta-epidemiology (narrow) | 0.001 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.001 | 0.001 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.001 | 0.001 |
| Open science | 0.001 | 0.001 |
| Research integrity | 0.001 | 0.001 |
| Insufficient payload (model declined to judge) | 0.002 | 0.001 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".