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Record W4417304493 · doi:10.1038/s41598-025-30688-w

Evaluating force and motion in posterior vitreous detachment manoeuvres using a robotic data acquisition system in cadaveric human eyes

2025· article· en· W4417304493 on OpenAlexaff
Reza Heidari, Esmaeil Asadi Khameneh, Ali Rastaghi, M. R. Dindarloo, Mohammad Mahdi Nazeri Ardakani, Mohammad Javad Ahmadi, Maryam Mohammadzadeh, Hamid Riazi‐Esfahani, Alireza Lashay, Mohammad Motaharifar, Seyed-Farzad Mohammadi, Mahdi Tavakoli, Hamid D. Taghirad

Bibliographic record

VenueScientific Reports · 2025
Typearticle
Languageen
FieldMedicine
TopicRetinal and Macular Surgery
Canadian institutionsUniversity of Alberta
FundersIran National Science Foundation
KeywordsCadaveric spasmTrajectoryData acquisitionCadaverMotion (physics)Sample (material)Motion analysisMotion capture

Abstract

fetched live from OpenAlex

Deep vitrectomy, a complex ophthalmic procedure, demands precise instrument control and remains challenging to master. This study evaluated the ARASH:ASiST robotic system as a platform for real-time, quantitative assessment of deep vitrectomy in a pre-clinical setting using cadaveric human eyes. The system records force and motion data without disrupting the surgical workflow. Cadaveric eyes were prepared under strict safety protocols, and a mannequin head with a customised eye holder was designed, refined through repeated testing, and approved by surgeons to fully imitate real-world conditions. Four surgeons with different levels of experience, defined by their years of practice, performed the “drunk walk” manoeuvre while intraoperative force, positional, and temporal data were captured. Despite the inherent limitations of human cadaveric eyes, the aim was to reproduce the drunk walk method as a precise, predefined trajectory for posterior vitreous detachment induction. In total, 14 surgical trials were recorded: 2 from one expert surgeon (right-handed), 4 from two fellows (right-handed), and 8 from one intermediate surgeon, who performed four procedures with each hand. Quantitative metrics, including Normalised Jerk, Force Range, Peak Force Magnitude, and Force RMS, were used to compare individual performances. Group-level comparisons between expert, fellow, and intermediate surgeons were conducted using ANOVA and Kruskal–Wallis tests. While not statistically significant, likely due to the limited sample size, the analysis of descriptive statistics and effect sizes indicated potential trends in performance metrics across experience levels, highlighting the feasibility of the platform for capturing such variations. During data acquisition, the robotic system’s remote-centre-of-motion was accurately calibrated with laser-based technology, while encoders and force sensors were also precisely calibrated. The system’s real-time graphical interface provided immediate feedback and enabled detailed postoperative analysis. Usability testing confirmed its practicality and non-intrusiveness. Overall, the ARASH:ASiST system demonstrates feasibility as an objective platform for the evaluation of deep vitrectomy based on ex vivo results. These findings support further validation of this prototype in synthetic and clinical environments.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.003
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.615
Threshold uncertainty score0.421

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0030.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.066
GPT teacher head0.379
Teacher spread0.313 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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