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Record W4417320261 · doi:10.7759/cureus.99261

Repetitive Transcranial Magnetic Stimulation Combined With Conventional Rehabilitation in a Patient With Lacunar Infarcts

2025· article· en· W4417320261 on OpenAlexaboutno aff
Ayesha Juhi, Shreya Sharma, Dinesh Bhatia, Suman Dhaka, Rajesh Kumar, Deepak Kumar, Pradosh Kumar Sarangi, Himel Mondal

Bibliographic record

VenueCureus · 2025
Typearticle
Languageen
FieldNeuroscience
TopicTranscranial Magnetic Stimulation Studies
Canadian institutionsnot available
FundersIndian Council of Medical Research
KeywordsTranscranial magnetic stimulationRehabilitationPrimary motor cortexCognitionMontreal Cognitive AssessmentMotor cortexStroke (engine)WeaknessDeep transcranial magnetic stimulationMagnetic resonance imaging

Abstract

fetched live from OpenAlex

Lacunar infarcts, though small, can produce significant motor and cognitive impairments due to their disruption of cortico-subcortical networks. This case report describes a 45-year-old woman with subacute to chronic ischemic lacunar infarcts involving the right frontal white matter, right thalamus, and left lentiform nucleus, who presented with left-sided weakness and mild cognitive deficits. The patient underwent a six-week rehabilitation program combining repetitive transcranial magnetic stimulation (rTMS) with conventional physiotherapy. Excitatory 10 Hz rTMS was applied over the ipsilesional (right) primary motor cortex (M1) for 30 sessions across six weeks, with five sessions per week, at an intensity of 80% RMT. Functional outcomes were evaluated using the Fugl-Meyer Assessment (FMA) for motor recovery and the Montreal Cognitive Assessment (MoCA) for cognition at baseline, mid-intervention, post-intervention, and three-month follow-up. The patient showed steady improvements, with FMA scores increasing from 27 to 43 (out of 66) for the upper limb and from 15 to 24 (out of 34) for the lower limb, while MoCA scores improved from 17 to 27 (out of 30). The gains were maintained at follow-up, and no adverse effects occurred during treatment. These findings suggest that combining rTMS with physiotherapy may enhance recovery in patients with lacunar infarcts by promoting cortical reorganization and interhemispheric balance. This case highlights the feasibility and clinical relevance of rTMS-based neurorehabilitation, even in resource-limited settings.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Case report · Consensus signal: Case report
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.003
Threshold uncertainty score0.005

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0010.001
Science and technology studies0.0010.001
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.010
GPT teacher head0.248
Teacher spread0.238 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designCase report
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes1
Has abstractyes

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