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Record W4417352997 · doi:10.1249/mss.0000000000003922

Improved Glycemic Control in Adults with Type 2 Diabetes Is More Strongly Associated with Exercise Duration than with Volume, Frequency, or Consistency

2025· article· en· W4417352997 on OpenAlexaff
Kylie D. Hesketh, Kaja Falkenhain, Joel Singer, Charlotte Jones, Catherine L. Russon, Matthew Cocks, Jonathan P. Little

Bibliographic record

VenueMedicine & Science in Sports & Exercise · 2025
Typearticle
Languageen
FieldMedicine
TopicCardiovascular and exercise physiology
Canadian institutionsOkanagan University CollegeKelowna General HospitalUniversity of British Columbia, Okanagan CampusUniversity of British Columbia
FundersMedical Research Council
KeywordsType 2 diabetesGlycemicDuration (music)Consistency (knowledge bases)Diabetes mellitusType 2 Diabetes Mellitus

Abstract

fetched live from OpenAlex

PURPOSE: Exercise interventions play a pivotal role in managing type 2 diabetes (T2D), yielding significant benefits in glycemic control. Despite the recognized role of exercise duration, volume, frequency, and consistency, the literature remains discrepant on which exerts the greatest effect. The purpose of this secondary analysis was to determine the relationship between exercise duration, volume, frequency, and consistency and markers of glycemic control (HbA1c and continuous glucose monitoring metrics) following a 26-wk mHealth intervention. METHODS: Inactive adults with newly diagnosed (<2 yr) T2D ( n = 58) completed blood and 14-day continuous glucose monitoring testing before and after a 26-wk personalized exercise intervention. Raw exercise data from fitness watches were extracted for each session. Duration, volume, frequency, and consistency were calculated for the full intervention and for the first 13 wk (greater support) and last 13 wk (reduced support). RESULTS: Average session duration (57 ± 36 min) significantly predicted HbA1c (β = -0.23 [0.07], P = 0.002), 24-h mean glucose (β = -0.03 [0.01], P = 0.01), and glycemic variability (standard deviation; β = -0.01 [0.0], P = 0.003; Beta coefficients are reported with standard errors). Total exercise time during the first 13 wk (2931 ± 3362 min) also predicted HbA1c (β = -0.001 [0.0], P = 0.01), mean glucose (β = -0.002 [0.0], P = 0.01), and glycemic variability (β = -0.005 [0.0], P = 0.03). No other exercise metrics significantly predicted outcomes. CONCLUSIONS: Average session duration and exercise time accumulated early in the intervention were the only significant predictors of improvements in HbA1c, mean glucose, and glucose variability. These findings suggest that promoting increased exercise duration, independent of type or intensity, may improve glycemic control among individuals with newly diagnosed T2D. TRIAL REGISTRATION: ClinicalTrials.gov NCT04653532.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.004
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.002
Threshold uncertainty score0.006

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.004
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.006
GPT teacher head0.237
Teacher spread0.231 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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