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Record W4417431233 · doi:10.1016/j.jcjp.2025.100278

The association between chondral lesions and patient-reported outcomes after meniscectomy: Data from the Osteoarthritis Initiative

2025· article· en· W4417431233 on OpenAlexaboutno aff
Ali Guermazi, Jamie E. Collins, Jared P. Sachs, Yusuf N Mufti, Brian J. Cole

Bibliographic record

VenueJournal of Cartilage & Joint Preservation · 2025
Typearticle
Languageen
FieldMedicine
TopicKnee injuries and reconstruction techniques
Canadian institutionsnot available
Fundersnot available
KeywordsWOMACOsteoarthritisLesionMagnetic resonance imagingKnee painConfidence intervalRadiography

Abstract

fetched live from OpenAlex

Introduction Evidence and guidelines around the treatment of meniscal tears in patients with knee osteoarthritis (OA) are conflicting, and the impact of chondral damage on surgical outcomes is unclear. Objective Our objective was to evaluate patient-reported outcomes (PROs) following meniscectomy and to determine whether the extent of chondral damage is associated with worse outcomes. Methods We utilized data from the Osteoarthritis Initiative and selected participants with radiographic knee OA (Kellgren-Lawrence grades 2 and 3) and magnetic resonance imaging (MRI) available. We identified the MRI before meniscectomy and measured lesion area on sagittal intermediate-weighted fat-suppressed and axial reformatted Double Echo Steady State MRI. The primary analysis included knees with pain in the year preceding arthroscopic surgery (Western Ontario and McMaster Universities Osteoarthritis Index [WOMAC] Pain > 20) and femoral lesion area >2 cm 2 . Secondary analysis included all knees. Results The primary analysis included 66 participants. Average improvements in PROs 2 years postsurgery were 13.2, 7.6, and 12.1 for WOMAC Pain, WOMAC Function, and Knee Injury and Osteoarthritis Outcome Score (KOOS) Pain, respectively. WOMAC Pain improvements were 10.6 (95% confidence interval: 2.3, 18.9) in those with femoral lesion area 2 to 9 cm 2 and 15.1 (95% confidence interval: 8.1, 22.0) in those with femoral lesion area ≥9 cm 2 . Results were consistent in secondary analyses. Conclusions Participants with radiographic knee OA undergoing meniscectomy reported improvements in PROs. Total femoral lesion area varied considerably, but we did not find associations between lesion area and PROs. These preliminary findings suggest that meniscectomy outcomes do not vary by chondral lesion extent in patients with Kellgren-Lawrence grades 2 and 3 OA.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.002
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.034
Threshold uncertainty score0.221

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.001
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.037
GPT teacher head0.303
Teacher spread0.266 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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