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Record W4417443086 · doi:10.2196/80710

Association of Skin Cancer With Clinical Depression and Poor Mental Health Days: Cross-Sectional Analysis

2025· article· en· W4417443086 on OpenAlexvenueno aff
Mytien Nguyen

Bibliographic record

VenueJMIR Dermatology · 2025
Typearticle
Languageen
FieldMedicine
TopicNonmelanoma Skin Cancer Studies
Canadian institutionsnot available
FundersYale University
KeywordsSkin cancerDepression (economics)Mental healthAssociation (psychology)DistressPsychological distress

Abstract

fetched live from OpenAlex

Background: Mental health is becoming increasingly recognized as an important part of overall health, especially for patients with cancer. However, the relationship between nonmelanoma skin cancer and mental health has not been widely studied. Objective: The aim of this study was to examine the association between nonmelanoma skin cancer diagnosis and 2 key mental health outcomes (ie, clinical depression and the number of poor mental health days). Methods: This study used the 2023 Behavioral Risk Factor Surveillance System, a nationally representative survey of adults in the United States, which included 312,317 participants. Nonmelanoma skin cancer diagnosis, depression, and self-reported mental health days were analyzed. Logistic regression was used to evaluate the association between nonmelanoma skin cancer and depression, whereas Poisson regression was used to model the number of poor mental health days, adjusting for age, sex, race and ethnicity, education, BMI, income, and major comorbid conditions (other cancers, heart disease, lung disease, and kidney disease). Results: Individuals with nonmelanoma skin cancer (5086/26,552, 19.15%) reported a lower overall rate of depression compared to those without nonmelanoma skin cancer (61,438/285,765, 21.50%; P<.001) but reported more poor mental health days on average (4.54, SD 8.37 d vs 3.20, SD 7.37 d; P<.001). After adjustment, nonmelanoma skin cancer diagnosis was not significantly associated with depression (adjusted odds ratio 1.01, 95% CI 0.98-1.05) and was associated with a slightly lower number of poor mental health days (adjusted rate ratio 0.94, 95% CI 0.91-0.97). Conclusions: Adults with nonmelanoma skin cancer experienced a meaningful mental health burden, and unadjusted analyses suggested greater day-to-day distress than among adults without nonmelanoma skin cancer. However, these differences were reduced and no longer significant for depression after adjusting for sociodemographic factors and comorbid chronic illnesses. These findings support the need for mental health screenings and support services in dermatologic and oncologic care.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.004
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.007
Threshold uncertainty score0.013

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0020.004
Meta-epidemiology (narrow)0.0000.001
Meta-epidemiology (broad)0.0000.001
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0010.001
Open science0.0010.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.018
GPT teacher head0.411
Teacher spread0.393 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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