Metabolic Consequences of Adverse Social Transitions among Aging Adults: A Gender-Sensitive Prospective Study of the Canadian Longitudinal Study on Aging Cohort (2011–2021)
Bibliographic record
Abstract
Background: Social connections impact morbidity and mortality, yet their influence on waist circumference (WC) and potential gender differences remains unclear. Methods: Prospective study of the Canadian Longitudinal Study on Aging (CLSA, 2011-2021) on changes in marital status, living arrangements, and social participation (baseline to follow-up 1) in relation to changes in WC (follow-up 1 to follow-up 2) used stratified, multivariable random coefficient regression with post-estimated predicted means. Sample sizes varied: 13,941 participants for marital and living arrangement transitions and 13,921 for changes in social participation. Results: Mean WC declined over time in aging cisgender heterosexual women and men in Canada. We found genders-specific associations between changes in different social connections changes in mean WC. Among women, decreased social participation was significantly associated with changes in WC (0.47 cm; 95 confidence interval [CI], 0.11 to 0.83), compared to women with stable social participation. Among men, becoming divorced was significantly associated with changes in WC (1.45 cm; 95% CI, 0.14 to 2.75), compared to men remained partnered. Women who decreased their social participation had a predicted mean WC of 87.61 cm (95% CI, 87.14 to 88.09), and men who became divorced had a predicted mean WC of 100.54 cm (95% CI, 99.17 to 101.91). Results for living arrangement changes were not significant, though patterned appeared gendered. All social connection transitions were associated with clinically meaningful predicted mean WC, placing both women and men with altered connections in the 'high risk' category for poor health outcomes. Conclusion: Decreased social participation increased WC among cisgender heterosexual women, whereas becoming divorced increased WC among cisgender heterosexual men in Canada.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.003 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.000 | 0.001 |
| Science and technology studies | 0.002 | 0.001 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.001 | 0.000 |
| Research integrity | 0.000 | 0.001 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".