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Record W4417458093 · doi:10.1177/08465371251398361

Imaging Methods for New-Onset Seizures at Canadian Pediatric Hospitals

2025· article· en· W4417458093 on OpenAlexafffundabout
Kate Hurley, Lucia Carpineta, Jean-Claude Décarie, Marc N. Elliott, Jonathan Grynspan, Naeem Khan, Pradeep Krishnan, Johanna Ortiz Jiménez, Yves Patenaude, Katya Rozovsky, Nina Stein, Makabongwe Tshuma, Xing‐Chang Wei, Daniela Pohl, Elka Miller

Bibliographic record

VenueCanadian Association of Radiologists Journal · 2025
Typearticle
Languageen
FieldMedicine
TopicAnesthesia and Sedative Agents
Canadian institutionsBC Children's HospitalMcMaster Children's HospitalUniversity of ManitobaCentre Hospitalier Universitaire de SherbrookeUniversité de MontréalHospital for Sick ChildrenCentre Hospitalier Universitaire Sainte-JustineDalhousie UniversityAlberta Children's HospitalSaskatchewan HealthJaneway Children's Health and Rehabilitation CentreQueen's UniversityMontreal Children's HospitalSaskatchewan Health AuthorityMcGill UniversityChildren's Hospital of Eastern Ontario
FundersEmployment and Social Development Canada
KeywordsSedationPediatric epilepsyMEDLINEPatient careNeuroimagingMagnetic resonance imaging

Abstract

fetched live from OpenAlex

BACKGROUND: Seizures are common neurological events in children, with neuroimaging playing a crucial role in evaluating new-onset seizures. While magnetic resonance imaging (MRI) is often preferred over computed tomography (CT) for pediatric seizure imaging due to higher sensitivity and lack of ionizing radiation, practices regarding imaging protocols and sedation use vary. Currently, there are no published Canada-wide guidelines describing the practices for workup of pediatric seizures. METHODS: A cross-sectional survey was conducted among radiologists at 16 Canadian tertiary pediatric centers to assess neuroimaging practices for children with new-onset seizures. The survey explored the presence and content of dedicated seizure MRI protocols, sedation use, and strategies to facilitate non-sedated MRI. RESULTS: Fifteen centers (94%) responded. Only 2 (13%) reported using dedicated new-onset seizure protocols, while 10 (67%) used epilepsy-specific MRI protocols, and the others used different approaches, including variations of routine brain MRI. MRI sequences varied across institutions. Sedation use also varied, with a median sedation age range of 3 months to 6 years. Non-sedated MRI techniques such as feed-and-swaddle (93%) and natural sleep (27%) were commonly used for infants. Video goggles (67%) and child life specialist support (53%) were often used for older children. Only 2 institutions (13%) had fast MRI protocols, and virtual reality preparation was uncommon (13%). CONCLUSION: Considerable variability exists in MRI protocols and sedation practices across Canadian pediatric centers evaluating new-onset seizures. Our findings emphasize the need for national consensus guidelines to standardize imaging protocols, reduce sedation use, and optimize care for pediatric seizure patients.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.016
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.089
Threshold uncertainty score0.223

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0020.016
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0030.004
Science and technology studies0.0030.001
Scholarly communication0.0010.001
Open science0.0020.001
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0080.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.016
GPT teacher head0.336
Teacher spread0.320 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes3
Has abstractyes

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