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3D Brain Imaging Using a Rotating Flat-Panel PET Scanner with LYSO/SiPM-Based Detectors

2025· article· W4417471627 on OpenAlexaff
Anirudh Shahi, Vasyl Komarov, Brandon Baldassi, F. Dodgson, Endi Benetti, Harutyun Poladyan, Edward Anashkin, Ur Metser, A. Reznik, Oleksandr Bubon

Bibliographic record

Venuenot available
Typearticle
Language
FieldMedicine
TopicMedical Imaging Techniques and Applications
Canadian institutionsThunder Bay Regional Research InstitutePrincess Margaret Cancer CentreLakehead University
Fundersnot available
KeywordsImaging phantomScannerImage resolutionBrain cancerIterative reconstructionDetectorNeuroimagingPositron emission tomographyBreast cancer

Abstract

fetched live from OpenAlex

Organ-targeted PET scanners offer improved spatial resolution, system sensitivity, and costefficiency compared to whole-body systems, and have shown promise especially in imaging breast cancer and Alzheimer's disease. While flat-panel scanners have enabled precise imaging of breast cancer lesions, their use in 3D brain imaging is constrained by the degraded axial spatial resolution due to incomplete angular coverage. Here, we present the first 3D image reconstructions of the Hoffman brain phantom acquired with a versatile LYSO/SiPM-based flat-panel PET scanner. We overcome the challenge of incomplete angular coverage by combining multi-angle acquisitions and performing composite image reconstructions.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.002
Threshold uncertainty score0.006

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0010.000
Open science0.0000.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0020.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.024
GPT teacher head0.322
Teacher spread0.298 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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