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A Comparative Analysis of ResNet-Based White Blood Cell Classification Across Multi-Scale Datasets for Enhanced Hematological Diagnostics

2025· article· W4417509236 on OpenAlexaff
Smita Nirkhi, Rajesh Gaikwad, Vijay Kumar Joshi, Syam Prasad Guda, Manish Motghare, Shashikant Patil

Bibliographic record

Venuenot available
Typearticle
Language
FieldComputer Science
TopicDigital Imaging for Blood Diseases
Canadian institutionsArtificial Intelligence in Medicine (Canada)
Fundersnot available
KeywordsGeneralizationPattern recognition (psychology)Domain (mathematical analysis)Deep learningClass (philosophy)Training setData modelingSupport vector machine

Abstract

fetched live from OpenAlex

In this proposed research work, we used the power of deep learning models, ResNetwork to correctly explore WBC. For implementation, six different datasets are collected. In Each datasets images are clicked from different angle and also a combined dataset is made. Some challenges are noticed while creating a new dataset of all the images. The disturbances in the images like overlapping cells and artifacts. ResNet can train the deep layers correctly, it lowers the problem of vanishing gradient. Combined data can enhance the generalization but the performance can be degraded due to versatility. Some classes work good on individual dataset but some typos are shown in rare classes like basophils or blasts. Domain adaptation, data augmentation and explainable AI are the possible suggestions to improve the model. A model alone is not enough for accurate WBC classification. Data variability, class imbalance, and interpretablity must also be handled. Only then can AI-based diagnostics become reliable and scalable.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.003
metaresearch head score (Gemma)0.004
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Simulation or modeling · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.008
Threshold uncertainty score0.016

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0030.004
Meta-epidemiology (narrow)0.0020.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0020.001
Science and technology studies0.0000.000
Scholarly communication0.0010.001
Open science0.0010.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0020.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.050
GPT teacher head0.364
Teacher spread0.313 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designSimulation or modeling
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations0
Published2025
Admission routes1
Has abstractyes

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