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Record W44800512 · doi:10.1177/070674370505000412

Lamotrigine-Induced Neutropenia

2005· letter· en· W44800512 on OpenAlexvenueno aff
Kellie LeDrew, Leslie Phillips, Maureen Hogan, Amanda MacCallum

Bibliographic record

VenueThe Canadian Journal of Psychiatry · 2005
Typeletter
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicBlood disorders and treatments
Canadian institutionsnot available
Fundersnot available
KeywordsLamotrigineNeutropeniaMedicinePsychiatryEpilepsyInternal medicineToxicity

Abstract

fetched live from OpenAlex

general (3).However, the use of antipsychotics in catatonia treatment is a contentious issue, given reports that high potency antipsychotics precipitated or exacerbated catatonia or neuroleptic malignant syndrome (NMS), a variant of malignant catatonia (3).In this regard, some authors suggest adjunctive use of a benzodiazepine while the antipsychotic drugs are being introduced, in the hope that a benzodiazepine may reduce the risk of NMS (6).We cannot ascertain whether this patient would have responded to higher dosages of lorazepam.However, the dosage this patient received is in the range used by other investigators to treat catatonia (2).While benzodiazepines, ECT, or atypical antipsychotics have been used to treat the acute phase of periodic catatonia, more research is needed on the duration of treating the acute phase with these modalities, as well as on the treatment of interepisode residual symptoms.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.007
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Case report · Consensus signal: Case report
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.019
Threshold uncertainty score0.045

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.007
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0010.001
Science and technology studies0.0020.001
Scholarly communication0.0010.001
Open science0.0010.000
Research integrity0.0150.011
Insufficient payload (model declined to judge)0.0070.002

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.010
GPT teacher head0.227
Teacher spread0.218 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designCase report
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations18
Published2005
Admission routes1
Has abstractno

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