Interaction between host cells and Salmonella Typhimurium isolates from septicemic pigs
Bibliographic record
Abstract
In this study, we characterized isolates (n=33) from septicemia outbreaks in swine herds as well as isolates (n=33) recovered from healthy animals at slaughter. At first, the rates of adhesion and invasion on intestinal epithelial cell lines were measured for all isolates. The isolates recovered from diseased animals have been shown to invade at a higher rate (P < 0.05) than isolates from healthy pigs. There was no significant difference for adhesion between 2 groups of isolates (P > 0.05). Some isolates were chosen for the remaining experiments according to invasion assay results. No difference between isolates from septicemic pigs and isolates from healthy pigs was detected for other phenotypic methods such as phagocytosis rates and survival in monocytes, apoptosis, adhesion to intestinal mucus and microbial surface properties. However, for the phagocytosis rates, a significant difference between the 2 groups of isolates was observed at 15 minutes (P < 0.05). These results suggest that early steps in the infection and spread within host phagocytes can be important in the outcome of the disease caused by these virulent isolates.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".