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Record W589183689 · doi:10.14264/107255

A study of canine lymphoid neoplasia

2005· dissertation· en· W589183689 on OpenAlexaboutno aff
Mark Quinnell

Bibliographic record

VenueThe University of Queensland · 2005
Typedissertation
Languageen
FieldMedicine
TopicVeterinary Oncology Research
Canadian institutionsnot available
Fundersnot available
KeywordsLymphomaPathologyMedicineLymphatic systemLymphLabrador Retriever

Abstract

fetched live from OpenAlex

This study involved an analysis of archived cases of canine lymphoid neoplasiafrom the University of Queensland Veterinary Pathology Laboratory from 1983 -2002. In addition, cases presented during the research period over the course of 2003were incorporated into the study. A total of 219 cases of lymphoid neoplasia were identified. These included 199 lymphomas, 18 tumours of plasma cell origin, and two acute lymphoblastic leukaemias. Through analysis of the archived signalment data for lymphoid neoplasia it was found that 46 different breeds were affected. The most commonly affected breeds were German shepherds (10.2%), boxers (6.5%), Labrador retrievers (6.0%), doberman pinschers (5.1%), and Staffordshire bull terriers (4.2%).The mean and median age of dogs with lymphoid neoplasia was 7 years and 9 months and 7 years and 10 months respectively, and the age range was 1 year and 4 months to 16 years and 10 months. The male to female ratio was 1.17:1. For canine lymphoma, the most commonly affected organs were lymph nodes (62.9% of cases), the liver(48.6% of cases), and the spleen (42.9% of cases). The multicentric form of the disease was the most frequent (45.7%), followed by the extranodal form (20.0%), the alimentary form (8.6%), and the mediastinal form (8.6%). A review of the cytological features of lymphomas in dogs found that they were morphologically diverse tumours, typically heterogeneous in appearance and with immature morphology. A review of histological specimens from cases of lymphoma in the archive found that these tumours frequently have a diffuse distribution and are composed of a population of cells exhibiting anisocytosis (mostly small to medium sized cells), and usually a low to moderate mitotic rate. Lymphomas composed of a homogenous cell population were all composed of small cells and generally had a low mitotic rate. In an immunohistochemical analysis of 35 biopsies, 4 cases had aputative B-cell phenotype and 7 had a putative T-cell phenotype.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.252
Threshold uncertainty score0.524

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.028
GPT teacher head0.308
Teacher spread0.280 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2005
Admission routes1
Has abstractyes

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