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Genomics and public health : legal and socio-ethical perspectives

2007· book· en· W641129702 on OpenAlexaboutno aff
Bartha Maria Knoppers

Bibliographic record

Venuenot available
Typebook
Languageen
FieldMedicine
TopicEthics in Clinical Research
Canadian institutionsnot available
Fundersnot available
KeywordsPublic healthBiobankNewborn screeningPopulationMedicinePolitical sciencePublic relationsFamily medicinePediatricsGeneticsEnvironmental healthPathologyBiology

Abstract

fetched live from OpenAlex

Acknowledgements -- Pt. I. Population screening: issues, realities and possibilities -- A Introduction: expansion of screening / J. Gerard Loeber -- Expansion of newborn screening: current achievements and new prospects / Bridget Wilcken -- Screening newborns for genetic susceptibility: what's the harm? / Nikki Kerruish -- Newborn screening expansion: Massachusetts research models encompass public health service responsibility / Anne Marie Comeau -- Carriers detected by neonatal screening: a clinical geneticist's view / Helena Kääriäinen and Ilona Autti-Rämö -- Systematic neonatal screening and carrier detection: lessons from sickle cell disease and cystic fibrosis screening in France / Jean-Louis Dhondt -- Carrier detection in newborns: should it be discovered? Should it be disclosed? Lessons from sickle cell anemia and cystic fibrosis screening in the United States / Lainie Friedman Ross, Carolyn and Matthew Bucksbaum -- B Introduction: newborn screening: storage and access for research / Ellen Wright Clayton -- The Danish newborn screening biobank in practice and research: revised biobank regulations / Bent Norgaard-Pedersen and David M. Hougaard -- Research and public health surveillance using newborn bloodspots in Canada / Denise Avard -- Implementation of population screening / Jane Halliday -- Pt. II. Balancing interests in public health genomics -- Introduction: Of genomics and public health: building public "goods "? / Bartha Maria Knoppers -- Privacy issues in public health genomics / Mark Rothstein and Herbert F. Boehl -- Balancing private and public interests in policy / Darren Shickle -- Public opinion, consent and population genetic biobanks / Timothy Caulfield and Nola M. Ries -- Challenges for public health genomics the public health perspective on genome-based knowledge and technologies / Angela Brand -- Pt. III. Genomics and public health: current approaches and future perspectives -- Introduction: The role of international stakeholders in genomics and public health / Andrea Boggio -- From genomic research to public health practice: international policy implications / Stuart Hogarth -- GRaPH Int: an international network for public health genomics / Alison Stewart, Mohamed Karmali, Ron Zimmern -- The role of international stakeholders patients as partners / Alastair Kent -- Genomics and modes of democratic dialogue: an analysis of two projects / Hubert Doucet, Marianne Dion-Labrie, Celine Durand and Isabelle Ganache -- Meeting of minds: a European citizen's deliberation on emerging technologies / Marie-Helene Mouneyrat -- Developments in genomics: engaging young people / Caroline Hurrent -- Interdisciplinary graduate training in public health genetics at the University of Washington / Melissa A. Austin

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.075
metaresearch head score (Gemma)0.057
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Other · Consensus signal: none
Teacher disagreement score0.075
Threshold uncertainty score0.398

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0750.057
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0020.001
Bibliometrics0.0020.002
Science and technology studies0.0150.111
Scholarly communication0.0250.025
Open science0.0040.013
Research integrity0.0380.037
Insufficient payload (model declined to judge)0.0080.002

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.460
GPT teacher head0.582
Teacher spread0.123 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreOther

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations10
Published2007
Admission routes1
Has abstractyes

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