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Effect of proprioceptive training combined with regular aerobic exercise on motor function in patients with Parkinson’s disease

2025· article· en· W6891718172 on OpenAlexaboutno aff

Bibliographic record

VenueDOAJ (DOAJ: Directory of Open Access Journals) · 2025
Typearticle
Languageen
FieldMedicine
TopicParkinson's Disease Mechanisms and Treatments
Canadian institutionsnot available
Fundersnot available
KeywordsProprioceptionAerobic exerciseCognitionBalance (ability)Montreal Cognitive AssessmentRehabilitationCenter of pressure (fluid mechanics)

Abstract

fetched live from OpenAlex

[Objective] To investigate the effects of proprioceptive training combined with regular aerobic exercise on motor symptoms, cognitive function and serum BDNF level in patients with Parkinson’s disease. [Methods] A total of 120 patients with Parkinson’s disease admitted to the Third Medical Center of Chinese PLA General Hospital from January 2023 to December 2023 were selected and divided into control group (n=60) and observation group (n=60) according to simple random method(single blind method). The control group only received routine intervention, and the observation group received proprioceptive training combined with regular aerobic exercise. Motor symptoms, cognitive function, serum BDNF level were assessed before and after intervention. [Results] The differences of TUGT time, Berg Balance Scale (BBS) score, length of movement track of pressure center and ellipse area of pressure center in observation group before and after intervention were greater than those in control group (P<0.05). After intervention, Montreal Cognitive Function Assessment Scale (MoCA) score, Mini-mental State Examination Scale (MMSE) score and difference of observation group were higher than those of control group (P<0.05). After intervention, the level and difference of BDNF in observation group were higher than those in control group (P<0.05). [Conclusion] Proprioceptive training combined with regular aerobic exercise can significantly improve motor symptoms and cognitive function in patients with Parkinson’s disease, and the mechanism may be related to the promotion of BDNF level.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Randomized trial · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.001
Threshold uncertainty score0.003

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.058
GPT teacher head0.427
Teacher spread0.369 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designRandomized trial
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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