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Additional file 1 of Fine dissection of limber pine resistance to Cronartium ribicola using targeted sequencing of the NLR family

2021· article· en· W6901899230 on OpenAlexaff

Bibliographic record

VenueFigshare · 2021
Typearticle
Languageen
FieldEnvironmental Science
TopicForest Insect Ecology and Management
Canadian institutionsNatural Resources Canada
Fundersnot available
KeywordsSingle-nucleotide polymorphismSNPMinor allele frequencyAlleleAllele frequencyGenotypeQuantitative trait locusGenetic linkage

Abstract

fetched live from OpenAlex

Additional file 1: Fig. S1. Distribution of minor allele frequency (MAF) of SNP loci detected in limber pine resistant gene analogs (RGAs). Fig. S2. SNP frequencies of limber pine resistance gene analogs (RGAs). Fig. S3. Sequencing depth of SNP loci in individual samples. The percentages of total SNPs (x-axis) have a coverage of a certain depth (y-axis). SNP depth was assessed in each individual of seed family LJ-112. The plot displays data for SNPs (967) with MAF ≥ 0.3 and about 70% of them have a minimum depth at 10 x in all samples except one. Fig. S4. The extent of missing data for 967 SNP loci in 96 individual samples of seed family LJ-112. Individual samples with missing data were calculated as a percentage of the total (y-axis) and plotted across the cumulative total SNPs (x-axis). Over 80% of total SNPs showed missing data in less than 10% of total individual samples. Fig. S5. Correlation of SNP positions of the same NLR gene mapped on the same linkage groups (LGs) by both Fluidigm amplicon-bases targeted-seq (TS) and whole exome-seq (WES). (a) Comparison of TS and WES in seed family LJ-112; (b) comparison of TS and WES between seed families LJ-112 and PHA-106. Fig. S6. Physical distances (bp) of paired SNPs mapped by Fluidigm amplicon-bases targeted-seq (TS) and whole exome-seq (WES). Fig. S7. Identification of NLR alleles significantly associated with MGR-conferred phenotypes using extreme-phenotype genome-wide association study (XP-GWAS). (a) Quantile–quantile plot of the test statistic: 5608 SNPs detected in 354 RGAs with coverage > 50 were subjected to association analysis. (b) Manhattan plot: top SNPs were selected for each genes and plotted against genetic maps of 12 linkage groups, and those genes not mapped so far were included as a separate group. Significant threshold value (p = 1.69 × 10− 4) is presented by a horizontal dash line.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.014
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesInsufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.835
Threshold uncertainty score0.235

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0020.014
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0020.001
Bibliometrics0.0020.003
Science and technology studies0.0010.000
Scholarly communication0.0020.002
Open science0.0030.001
Research integrity0.0020.001
Insufficient payload (model declined to judge)0.8350.165

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.021
GPT teacher head0.215
Teacher spread0.194 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2021
Admission routes1
Has abstractyes

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