Additional file 8 of Soluble CX3CL1-expressing retinal pigment epithelium cells protect rod photoreceptors in a mouse model of retinitis pigmentosa
Bibliographic record
Abstract
Additional file 8. Fig. S7 Photoreceptor preservation in the rd10 mouse is not observed on PN35. Rd10 mice were treated on PN14, prior to the onset of rod degeneration, with subretinal injections of FS-Luc or FS-CX3-9 hRPE in HAMC, or HAMC alone (sham). Mice were sacrificed on PN35 for analysis. A Retinas immunostained for s-opsin. mCherry fluorescent reporter is expressed by injected cells. B Quantification of rows of nuclei (n = 3–4 eyes, each consisting of 3 technical replicates or tissue sections analyzed). Scale is 50 µm. One-way ANOVA and Tukey’s post-hoc analysis performed for statistical analysis. All comparisons are not statistically significant. ONL, outer nuclear layer; SRS, subretinal space.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.002 | 0.013 |
| Meta-epidemiology (narrow) | 0.001 | 0.001 |
| Meta-epidemiology (broad) | 0.002 | 0.001 |
| Bibliometrics | 0.002 | 0.002 |
| Science and technology studies | 0.001 | 0.000 |
| Scholarly communication | 0.002 | 0.002 |
| Open science | 0.002 | 0.001 |
| Research integrity | 0.001 | 0.001 |
| Insufficient payload (model declined to judge) | 0.892 | 0.234 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".