Additional file 3: of Selective serotonin reuptake inhibitor use during early pregnancy and congenital malformations: a systematic review and meta-analysis of cohort studies of more than 9 million births
Bibliographic record
Abstract
Table S1. EUBOCAT Guide 1.3, ICD-10, and ICD-9 codes used to identify and define congenital malformations. Table S2. Characteristics of cohort studies of selective serotonin reuptake inhibitors (SSRIs) use in first-trimester and congenital malformations. Table S3. Risk of bias of included reports from cohort studies as assessed with the Newcastle-Ottawa scale. Table S4. Exposure to selective serotonin reuptake inhibitors (SSRIs) during the first trimester of pregnancy and risk of congenital malformations in infants: results of meta-analyses. Table S5. Exposure to citalopram during the first trimester of pregnancy and risk of congenital malformations in infants: results of meta-analyses. Table S6. Exposure to fluoxetine during the first trimester of pregnancy and risk of congenital malformations in infants: results of meta-analyses. Table S7. Exposure to paroxetine during the first trimester of pregnancy and risk of congenital malformations in infants: results of meta-analyses. Table S8. Exposure to sertraline during the first trimester of pregnancy and risk of congenital malformations in infants: results of meta-analyses. Table S9. Exposure to escitalopram during the first trimester of pregnancy and risk of congenital malformations in infants: results of meta-analyses. Table S10. Exposure to fluvoxamine during the first trimester of pregnancy and risk of congenital malformations in infants: results of meta-analyses. Table S11. Subgroup analysis of selective serotonin reuptake inhibitors (SSRIs) and risk of congenital malformations in infants: results of meta-analyses. Table S12. Subgroup analysis of citalopram and risk of congenital malformations in infants: results of meta-analyses. Table S13. Subgroup analysis of fluoxetine and risk of congenital malformations in infants: results of meta-analyses. Table S14. Subgroup analysis of paroxetine and risk of congenital malformations in infants: results of meta-analyses. Table S15. Subgroup analysis of sertraline and risk of congenital malformations in infants: results of meta-analyses. (DOC 1162 kb)
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.004 | 0.059 |
| Meta-epidemiology (narrow) | 0.002 | 0.001 |
| Meta-epidemiology (broad) | 0.005 | 0.007 |
| Bibliometrics | 0.006 | 0.010 |
| Science and technology studies | 0.001 | 0.000 |
| Scholarly communication | 0.002 | 0.004 |
| Open science | 0.002 | 0.001 |
| Research integrity | 0.002 | 0.001 |
| Insufficient payload (model declined to judge) | 0.627 | 0.018 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".