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Record W6906483790 · doi:10.17863/cam.44881

Low-frequency variation in TP53 has large effects on head circumference and intracranial volume.

2019· article· en· W6906483790 on OpenAlexfundno aff

Bibliographic record

VenueApollo (University of Cambridge) · 2019
Typearticle
Languageen
FieldMedicine
TopicCancer-related Molecular Pathways
Canadian institutionsnot available
FundersNIHR Cambridge Biomedical Research CentreDepartment of Epidemiology, Biostatistics and Occupational Health, McGill UniversityInstitute of Psychiatry, Psychology and Neuroscience, King’s College LondonUniversitätsklinikum KölnQueen's UniversityUniversity of BristolUniversity of GlasgowMedical Research CouncilUniversity of SussexUniversity of OxfordJewish General HospitalKing's College LondonDiamantina Institute, University of QueenslandUniversity of LeicesterWellcome TrustUniversity College LondonBritish Heart FoundationUniversidade de LisboaBroad InstituteTerveyden ja hyvinvoinnin laitosEuropean Molecular Biology LaboratoryCardiff UniversityEli Lilly and CompanyNational Cancer Research InstituteCancer Research InstituteMcGill UniversityHelsingin YliopistoAdaptive BiotechnologiesNational Institute for Health and Care ResearchQueen Mary University of LondonSussex Partnership NHS Foundation TrustBiogenUniversity of EdinburghDavid Geffen School of Medicine, University of California, Los AngelesMassachusetts General Hospital
KeywordsNucleofectionTSG101HyporeflexiaGestational periodDiafiltrationProteogenomicsArticular cartilage damage

Abstract

fetched live from OpenAlex
No abstract in any covered source. Its absence is recorded, not treated as a negative.

No abstract. This is not a gap in this database; OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.780
Threshold uncertainty score0.685

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.006
GPT teacher head0.195
Teacher spread0.189 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2019
Admission routes1
Has abstractno

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