The Impacts of Xinglou Tongluo Drink Combined with Clopidogrel on Cognitive Function, Cerebral Blood Circulation, and Serum Netrin-1 Level in Patients with ElderlyAcute Sschemic Stroke
Bibliographic record
Abstract
Objective To investigate the impacts of Xinglou Tongluo drink combined with clopidogrel on cognitive function, cerebral blood circulation, and serum Netrin-1 level in elderly patients with acute ischemic stroke. Methods A total of 80 elderly patients with acute ischemic stroke admitted to Handan Central Hospital from January 2022 to May 2023 were selected as the study subjects.They were randomly divided into an observation group(40 cases) and a control group(40 cases) using a random number table method.The control group received treatment with clopidogrel, while the observation group received treatment with Xinglou Tongluo Yin combined with clopidogrel.The clinical efficacy, cerebral blood circulation indicators [blood flow resistance index(RI), mean blood flow velocity(Vm), and vascular pulsatility index(PI)] , serum indicators [Netrin-1 and matrix metalloproteinase-9] and Neurological function [National Institutes of Health Stroke Scale(NIHSS) score] and cognitive function [Montreal Cognitive Assessment Scale(MoCA) score] were compared between the two groups. Results The overall response rate in the observation group was higher than that in the control group(P<0.05);after treatment, RI and PI decreased and Vm increased in both groups, and RI and PI in the observation group were lower than those in the control group, Vm was higher than that in the control group, and the differences were statistically significant(P<0.05);after treatment, Netrin-1 increased and MMP-9 decreased in both groups, and Netrin-1 was higher and MMP-9 was lower in the observation group than in the control group, and the differences were statistically significant(P<0.05);after treatment, NIHSS score decreased and MoCA score increased in both groups, and the NIHSS score in the observation group was lower than that in the control group, MoCA score was higher than that in the control group, and the differences were statistically significant(P<0.05). Conclusion Xinglou Tongluo drink combined with clopidogrel can effectively improve cognitive function and serum Netrin-1 level in elderly patients with acute ischemic stroke, and improve cerebral blood circulation.
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.001 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.001 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".