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Record W6910587907 · doi:10.48448/pntx-vj23

Neuronal sensitivity and variability mediate 3 parallel strategies for encoding natural translations in the primate vestibular system

2021· other· en· W6910587907 on OpenAlexaff

Bibliographic record

VenueUnderline Science Inc. · 2021
Typeother
Languageen
Field
Topic
Canadian institutionsMcGill University
Fundersnot available
KeywordsPrimateStimulus (psychology)Vestibular systemContext (archaeology)Redundancy (engineering)Encoding (memory)Translation (biology)OtolithNatural sounds

Abstract

fetched live from OpenAlex

Self motion is composed of both rotational and translational motions which occur with characteristic statistics in everyday life. In the context of rotation, we have previously shown that neurons at the first central stage of vestibular processing (VN) are adapted to match their tuning curves to the statistics of natural rotation. This strategy effectively removes redundancy in the neural response, and produces responses which are independent of frequency (i.e. temporally whitened). However, unlike for rotation, translation sensitive neurons display significantly more heterogeneity in their tuning curves to artificial stimuli, and their responses to natural stimuli which cover the full physiological range of motion frequencies has not been explored. Here we investigated whether and, if so, how the responses of translation sensitive vestibular-only (otolith VO) cells in the VN of awake behaving macaques are adapted to naturalistic translation stimuli. Our results indicate that otolith VOs are not consistently matched to natural statistics in the same way as their rotation-sensitive counterparts, and instead fall roughly into 3 categories covering a range from strongly low-pass filtered to optimally whitened responses. This study is the first to examine the responses of otolith VO neurons in the context of natural self-motion, and suggests that low-pass filtered, faithful reconstruction, and optimally encoded representations of the stimulus may each be implemented in the translational vestibular system via parallel encoding strategies.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.006
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Simulation or modeling · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.931
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0060.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.001
Science and technology studies0.0000.002
Scholarly communication0.0010.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.029
GPT teacher head0.307
Teacher spread0.278 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designSimulation or modeling
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2021
Admission routes1
Has abstractyes

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