Additional file 3 of Channel nuclear pore protein 54 directs sexual differentiation and neuronal wiring of female reproductive behaviors in Drosophila
Bibliographic record
Abstract
Additional file 3 Nup54 RNAi in doublesex expressing neurons reveals a separable sex-peptide response in receptivity and oviposition and a role in sexual differentiation. A) Receptivity after Nup54 RNAi knock-down from UAS P{GD14041}v42153; P{GD14041}v42154 inserts in neurons with elavGAL4C155 (yellow) and in ppkGAL4 (orange), fruGAL4 (green) and dsxGAL4 (red) patterns after sex-peptide (SP, dark color) or Ringer’s (R, light color) injection measured by counting mating females in a 1 h time period 3 h after SP or R injection, respectively. Means with the standard error for three experiments with 16 females each are shown, and statistically significant differences from ANOVA post-hoc pairwise comparisons are indicated by different letters (p≤0.001). B) Oviposition after Nup54 RNAi knock-down from UAS P{GD14041}v42153; P{GD14041}v42154 inserts in neurons with elavGAL4C155 (yellow) and in ppkGAL4 (orange), fruGAL4 (green) and dsxGAL4 (red) patterns after sex-peptide (SP, dark color) or Ringer’s (R, light color) injection shown as means of eggs laid in 18 h with the standard error for 8 females each, respectively, and statistically significant differences from ANOVA post-hoc pairwise comparisons are indicated by different letters (p≤0.0001). C, D) Genitals of control females (C) and females expressing Nup62 RNAi from UAS with dsxGAL4 (D). The scale bar in C is 20 μm. E, F) Front legs of control males (E) and males expressing Nup62 RNAi from UAS with dsxGAL4 (F). Arrowheads indicate the position of sex combs. The scale bar in E is 100 μm. The data underlying the presented graphs are in Additional file 6.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.314 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".