Additional file 1 of Enhanced prefrontal nicotinic signaling as evidence of active compensation in Alzheimer’s disease models
Bibliographic record
Abstract
Additional file 1: Table S1 Neuronal intrinsic properties of layer 6 pyramidal neurons by genotype in mice. Table S2 Neuronal intrinsic properties of layer 6 pyramidal neurons by genotype in rats. Figure S1 There are no significant differences in intrinsic excitability between nTg and TgCRND8 layer 6 pyramidal neurons in mouse. Figure S2 Decrease in intrinsic excitability between F344 and TgF344 layer 6 pyramidal neurons in mid disease. Figure S3 Cholinergic treatments are consistently effective in prefrontal layer 6 pyramidal neurons of TgCRND8 AD and nTg controls. Figure S4 Cholinergic treatments are consistently effective at early to mid-AD and late-AD in layer 6 pyramidal neurons of prefrontal cortex
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.002 | 0.017 |
| Meta-epidemiology (narrow) | 0.001 | 0.001 |
| Meta-epidemiology (broad) | 0.001 | 0.001 |
| Bibliometrics | 0.002 | 0.003 |
| Science and technology studies | 0.001 | 0.000 |
| Scholarly communication | 0.001 | 0.001 |
| Open science | 0.002 | 0.001 |
| Research integrity | 0.001 | 0.001 |
| Insufficient payload (model declined to judge) | 0.872 | 0.159 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".