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Association of the <i>MC4R</i> rs17782313 with endometrial carcinoma risk in non-Hispanic white women.

2015· other· en· W6923183049 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

aboutThe title or abstract carries a Canadian signal from the geographic lexicon.
no affNo Canadian affiliation: this work is invisible to an affiliation-only frame.
No Canadian affiliation. An affiliation-only frame, the usual design, would never have seen this work. It is one of the works that make the case for inverting the frame.

Bibliographic record

VenueFigshare · 2015
Typeother
Languageen
FieldComputer Science
TopicEducational Robotics and Engineering
Canadian institutionsnot available
Fundersnot available
KeywordsEndometrial cancerAlleleCarcinomaProportional hazards modelIncidence (geometry)Risk factorCase-control study

Abstract

fetched live from OpenAlex

<p>Forest plot of the ORs and 95% CIs comparing endometrial carcinoma risk for the <i>MC4R</i> rs17782313 rare allele homozygotes (CC genotype) versus common allele homozygotes (<i>TT</i> genotype) for eight studies included in the pooled analysis. The pooled<sup>a</sup> OR for all studies combined was 0.97 [95% CI: 0.81–1.18; p (1 d.f.) = 0.78]. P for heterogeneity of effects by study = 0.49. The pooled<sup>b</sup> OR for studies including incident cases only (excluding TORONTO study) was 0.99 [95% CI: 0.81–1.22; p (1 d.f.) = 0.94]. P for heterogeneity of effects between studies with incident cases vs. prevalent cases (TORONTO) = 0.68. Pooling was performed by combining all data using study as fixed and random effects (results were the same).</p>

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesInsufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Other · Consensus signal: Other
Teacher disagreement score0.263
Threshold uncertainty score0.994

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0010.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0070.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.012
GPT teacher head0.206
Teacher spread0.195 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it