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Record W6929028064 · doi:10.4224/crm.2021.smt1-1

SMT1-1: SARS-CoV-2 Spike Glycoprotein Reference Material

2021· other· en· W6929028064 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueNRC Digital Repository · 2021
Typeother
Languageen
Field
Topic
Canadian institutionsNational Research Council Canada
Fundersnot available
KeywordsSpike (software development)GlycoproteinSodiumMolecular mass

Abstract

fetched live from OpenAlex

SMT1-1 is a reference material (RM) designed for the development of SARS-CoV-2 spike glycoprotein detection methods, as well as an antigen source for use in SARS-CoV-2 immunological assays. The majority of available SARS-CoV-2 test kits and vaccines exploit the interaction between the SARS-CoV-2 spike glycoprotein and human anti-spike antibodies. Reference values for the molar concentration, mass fraction, and mass concentration of SARS-CoV-2 spike glycoprotein in SMT1-1 have been established. Values are provided for the known spike protein sequence region that ignores the glycan, and also the full spike glycoprotein where the mass fraction and mass concentration values include an estimate of the molar mass of the glycan. Information values for the size heterogeneity of SARS-CoV-2 spike glycoprotein in SMT1-1 are provided. A unit of SMT1-1 contains 1.2 mL of SARS-CoV-2 spike glycoprotein in Dulbecco's phosphate-buffered saline (DPBS) with 10 mM HEPES sodium salt.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow), Scholarly communication, Insufficient payload (model declined to judge)
Consensus categoriesInsufficient payload (model declined to judge)
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Other · Consensus signal: Other
Teacher disagreement score0.102
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0020.000
Open science0.0010.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0010.007

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.026
GPT teacher head0.264
Teacher spread0.237 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Quick stats

Citations3
Published2021
Admission routes1
Has abstractyes

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