MétaCan
Menu
Back to cohort
Record W6931672917 · doi:10.5281/zenodo.8194413

Fig. 8 in Metabolites isolated from the human intestinal fungus Penicillium oxalicum SL2 and their agonistic effects on PXR and FXR

2022· other· en· W6931672917 on OpenAlexaff

Bibliographic record

VenueZenodo (CERN European Organization for Nuclear Research) · 2022
Typeother
Languageen
FieldDecision Sciences
TopicReliability and Agreement in Measurement
Canadian institutionsCAE (Canada)
Fundersnot available
KeywordsAgonistic behaviourPregnane X receptorMutantMetaboliteFungusStrain (injury)Structure–activity relationship

Abstract

fetched live from OpenAlex

Fig. 8. (A) The 3D structure and hydrogen bond interaction of compound 18 with FXR at the 50th ns MD stimulation. (B) The agonistic activity of compound 18 against the wild-type, mutant R341V, or S342V FXR. Data were shown as the mean ± SD, n = 4 (*p <0.05, **p <0.01, ***p <0.001 compared to the Ctrl group; #p <0.05, ##p <0.01, ###p <0.001 compared to the WT group).

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.003
metaresearch head score (Gemma)0.004
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesScience and technology studies, Scholarly communication, Insufficient payload (model declined to judge)
Consensus categoriesInsufficient payload (model declined to judge)
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.770
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0030.004
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.001
Science and technology studies0.0010.000
Scholarly communication0.0010.000
Open science0.0020.002
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0420.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.076
GPT teacher head0.296
Teacher spread0.220 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; both teacher heads agree on what is shown here.

Study designNot applicable
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2022
Admission routes1
Has abstractyes

Explore more

Same venueZenodo (CERN European Organization for Nuclear Research)Same topicReliability and Agreement in MeasurementFrench-language works237,207