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Record W6932047131 · doi:10.5281/zenodo.8317843

Summary statistics of the X-chromosome for 2,822 brain imaging traits in UKB (n = 34,000)

2024· article· en· W6932047131 on OpenAlexaff

Bibliographic record

VenueZenodo (CERN European Organization for Nuclear Research) · 2024
Typearticle
Languageen
FieldMedicine
TopicCardiovascular Health and Disease Prevention
Canadian institutionsUniversity of Toronto
Fundersnot available
KeywordsAssociation (psychology)NeuroimagingHuman brainMagnetic resonance imagingBrain mappingBrain sizeGenome-wide association studyWhite matter

Abstract

fetched live from OpenAlex

This deposit hosts X-chromosome association summary statistics using 34,000 UKB white subjects for 2,822 brain imaging traits, including 101 regional brain volume traits, 63 cortical thickness traits, 66 surface area traits, 525 DTI PC traits, 110 DTI tract-mean traits, 1,777 ICA resting-state functional MRI (rfMRI) traits, 90 Glasser360 mean-level rfMRI traits, and 90 Glasser360 mean-level task-evoked functional MRI (trfMRI) traits. The shared data includes: 1. sex-agnostic association analysis for X-chr (PAR and NPR) 2. sex-stratified association analysis for X-chr (PAR and NPR) The corresponding article: Jiang, Zhiwen, et al. "The pivotal role of the X-chromosome in the genetic architecture of the human brain." medRxiv (2023): 2023-08.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.006
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.012
Threshold uncertainty score0.039

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.006
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0020.002
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.001
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0120.003

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.022
GPT teacher head0.280
Teacher spread0.257 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2024
Admission routes1
Has abstractyes

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