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Additional file 1 of Genetic predisposition to longer telomere length and risk of childhood, adolescent and adult-onset ependymoma

2020· article· en· W6938947971 on OpenAlexaffabout

Bibliographic record

VenueOpen MIND · 2020
Typearticle
Languageen
FieldMedicine
TopicGlioma Diagnosis and Treatment
Canadian institutionsSickKids FoundationHospital for Sick Children
Fundersnot available
KeywordsEpendymomaSNPTelomereLinkage (software)Genetic predispositionTable (database)Single-nucleotide polymorphismGenetic association

Abstract

fetched live from OpenAlex

Additional file 1: Supplementary note: The Glioma International Case Control Study membership. Supplementary Table 1. Demographic and clinical data for pediatric ependymoma cases (ages 0-19) from the California Cancer Record Linkage Project (CCRLP). Supplementary Table 2. Single SNP associations between LTL-associated variants and ependymoma risk in the CCRLP case-control dataset, stratified by age at diagnosis. Supplementary Table 3. Single SNP associations between LTL-associated variants and ependymoma risk in the Toronto and GICC case-control datasets. Supplementary Table 4. Association between polygenic score for longer leukocyte telomere length and risk of ependymoma in the California Cancer Records Linkage Project (CCRLP)a, stratified by tumor site (spinal vs. intracranial) and age (<12, ≥12). Associations are adjusted for sex and first 10 principal components

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.029
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesInsufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Other · Consensus signal: none
Teacher disagreement score0.826
Threshold uncertainty score0.248

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.029
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0020.004
Science and technology studies0.0010.000
Scholarly communication0.0010.002
Open science0.0020.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.8260.094

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.013
GPT teacher head0.243
Teacher spread0.230 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

Study designNot applicable
Domainnot available
GenreOther

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2020
Admission routes2
Has abstractyes

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