MICCAI 2018 – Computational Precision Medicine Challenge: 18F-FDG PET Radiomics Risk Stratifiers in Head and Neck Cancer
Bibliographic record
Abstract
The Computational Precision Medicine (CPM) 2018 was held on September 16, in Granada (Spain), in conjunction with MICCAI 2018. As part of the CPM program, a series of imaging Grand Challenges were offered, hosted by kaggle. This competition, "18F-FDG PET Radiomics Risk Stratifiers in Head and Neck Cancer", was organized as a Medical Image Computing and Computer Assisted Intervention (MICCAI) Computational Precision Medicine (CPM) grand challenge. Contestants weretasked to predict, using primary tumor 18F-FDG PET-derived radiomics features +/- matched clinical data, whether a tumor arising from the oropharynx will be controlled by definitive radiation treatment (RT). The head and neck radiation oncology team from University of Texas MD Anderson Cancer Center (MDACC) have curated and harmonized a multi-institutional dataset of 248 oropharynx cancer (OPC) patients, using our in-house 'LAMBDA-RAD' data management platform. Scans came from six different institutes from: the US (MDACC), Canada [four different clinical institutions in Québec: Hôpital Général Juif de Montréal (HGJ), Centre Hospitalier Universitaire de Sherbrooke (CHUS), Centre Hopitalier de l'Université de Montréal (CHUM) and Hôpital Maisonneuve-Rosemont de Montréal (HMR)], and Europe (MAASTRO Clinic, The Netherlands). The challenge was open from June 15, 2018, 11:59 p.m. toAug. 30, 2018, midnight UT; this repository serves as FAIR (re)use durable repository for challenge data. Details on the 2018 CPM Challenges can be found at: https://wiki.cancerimagingarchive.net/pages/viewpage.action?pageId=37224869 The "18F-FDG PET Radiomics Risk Stratifiers in Head and Neck Cancer" challenge website (archived) can be viewed at: https://web.archive.org/web/20190106050801/http://miccai.cloudapp.net/competitions/77and at: https://web.archive.org/web/20210418000112/https://wiki.cancerimagingarchive.net/pages/viewpage.action?pageId=37224869 The kaggle-in-class host page for the challenge and results can be found at: https://www.kaggle.com/c/pet-radiomics-challenges.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.015 | 0.027 |
| Meta-epidemiology (narrow) | 0.003 | 0.001 |
| Meta-epidemiology (broad) | 0.004 | 0.003 |
| Bibliometrics | 0.003 | 0.003 |
| Science and technology studies | 0.001 | 0.002 |
| Scholarly communication | 0.006 | 0.002 |
| Open science | 0.005 | 0.005 |
| Research integrity | 0.005 | 0.005 |
| Insufficient payload (model declined to judge) | 0.006 | 0.003 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".