Additional file 1 of Real world evidence of the association between medication and life expectancy in elderly inflammatory bowel disease: a population-based cohort study
Bibliographic record
Abstract
Additional file 1. Table S1. List of drug identification numbers used to identify medications included in this study. Table S2. List of validated codes used to identify patients requiring small bowel resection (Crohn’s disease) or colectomy (Crohn’s disease and ulcerative colitis). Table S3. Differences in life expectancy at 65 years comparing medications used to treat Crohn’s disease in seniors. Differences correspond to the medication referenced in the column name subtracted from the medication reference in the row name (i.e., LErow – LEcolumn). Significant differences are indicated in bold font. Table S4. Differences in life expectancy at 65 years comparing medications used to treat ulcerative colitis in seniors. Differences correspond to the medication referenced in the column name subtracted from the medication reference in the row name (i.e., LErow – LEcolumn). Significant differences are indicated in bold font. Table S5. Differences in life expectancy at 65 years comparing medications used to treat Crohn’s disease in seniors, censoring at intestinal resection or colectomy. Differences correspond to the medication referenced in the column name subtracted from the medication reference in the row name (i.e., LErow – LEcolumn). Significant differences are indicated in bold font. Table S6. Differences in life expectancy at 65 years comparing medications used to treat ulcerative colitis in seniors, censoring at colectomy. Differences correspond to the medication referenced in the column name subtracted from the medication reference in the row name (i.e., LErow – LEcolumn). Significant differences are indicated in bold font. Figure S1. Life expectancy at 65 years of age in (A) females and (B) males with Crohn’s disease, stratified by type of medical treatment. Figure S2. The proportion of people expected to be alive at each age interval based on type of medical treatment in (A) females and (B) males with Crohn’s disease. Figure S3. Life expectancy at 65 years of age in (A) females and (B) males with ulcerative colitis, stratified by type of medical treatment. Figure S4. The proportion of people expected to be alive at each age interval based on type of medical treatment in (A) females and (B) males with ulcerative colitis.Figure S5. Life expectancy at 65 years of age in (A) females and (B) males with Crohn’s disease, stratified by type of medical treatment and censored at intestinal resection or surgery. Figure S6. Life expectancy at 65 years of age in (A) females and (B) males with ulcerative colitis, stratified by type of medical treatment and censored at colectomy. Figure S7. The proportion of people expected to be alive at each age interval based on type of medical treatment in (A) females and (B) males with Crohn’s disease, censored at intestinal resection or colectomy. Figure S8. The proportion of people expected to be alive at each age interval based on type of medical treatment in (A) females and (B) males with ulcerative colitis, censoring at colectomy.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.002 | 0.041 |
| Meta-epidemiology (narrow) | 0.001 | 0.001 |
| Meta-epidemiology (broad) | 0.002 | 0.001 |
| Bibliometrics | 0.002 | 0.006 |
| Science and technology studies | 0.001 | 0.000 |
| Scholarly communication | 0.001 | 0.002 |
| Open science | 0.001 | 0.001 |
| Research integrity | 0.001 | 0.001 |
| Insufficient payload (model declined to judge) | 0.653 | 0.036 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".